N4-Cyclopropyl-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

Base Information

Chemical Name:N4-Cyclopropyl-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
CAS No.:443642-41-9
Molecular Formula:C₁₅H₂₁N₅O₄
Molecular Weight:335.363
Hs Code.:
Mol file:443642-41-9.mol

Synonyms:7H-PYRROLO[2,3-D]PYRIMIDINE-2,4-DIAMINE,N4-CYCLOPROPYL-7-(2-C-METHYL-B-D-RIBOFURANOSYL)-;

Suppliers and Price of N4-Cyclopropyl-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of N4-Cyclopropyl-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

Chemical Property:

PSA：138.68000
LogP:0.24360

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N4-Cyclopropyl-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

There total 7 articles about N4-Cyclopropyl-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 443642-40-8
2-amino-4-chloro-7-[2-C-methyl-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine

: 443642-41-9
2-amino-4-cyclopropylamino-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: In Cyclopropylamine;

Reference yield:

: 765-30-0
Cyclopropylamine

: 443642-40-8
2-amino-4-chloro-7-[2-C-methyl-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine

: 443642-41-9
2-amino-4-cyclopropylamino-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: at 70 ℃; for 48h;

Reference yield:

: 168427-36-9
2-O-acetyl-3,5-bis-O-(2,4-dichlorophenylmethyl)-1-O-methyl-α-D-ribofuranose

: 443642-41-9
2-amino-4-cyclopropylamino-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 6 steps

1.1: methanol; potassium carbonate / 0.75 h / 20 °C

2.1: Dess-Martin periodane / dichloromethane / 73 h / 0 - 20 °C / Inert atmosphere

3.1: diethyl ether / 7 h / -55 - -15 °C

3.2: 0.5 h / 20 °C / Cooling with ice

4.1: hydrogen bromide; acetic acid / dichloromethane / 2 h / 20 °C

4.2: 1 h / 20 °C

5.1: boron trichloride / dichloromethane / 4.5 h / -78 - -20 °C

6.1: 48 h / 70 °C

With methanol; hydrogen bromide; boron trichloride; potassium carbonate; Dess-Martin periodane; acetic acid; In diethyl ether; dichloromethane;