(R)-Methyl 3-hydroxy-2-methylpropanoate

Base Information Edit

Chemical Name:(R)-Methyl 3-hydroxy-2-methylpropanoate
CAS No.:72657-23-9
Molecular Formula:C5H10 O3
Molecular Weight:118.133
Hs Code.:29181990
UNII:569FQ3X7KG
DSSTox Substance ID:DTXSID90993497
Nikkaji Number:J61.908F
Wikipedia:Roche_ester
Wikidata:Q72491391
Mol file:72657-23-9.mol

Synonyms:72657-23-9;(R)-Methyl 3-hydroxy-2-methylpropanoate;(R)-(-)-3-Hydroxy-2-methylpropionic acid methyl ester;Methyl (R)-(-)-3-hydroxy-2-methylpropionate;methyl (2R)-3-hydroxy-2-methylpropanoate;Methyl (R)-3-hydroxy-2-methylpropionate;R-(-)-Roche Ester;(R)-3-HYDROXYISOBUTYRIC ACID METHYL ESTER;Propanoic acid, 3-hydroxy-2-methyl-, methyl ester, (2R)-;ROCHE ESTER;Roche ester, (R)-;(-)-(R)-Roche ester;Methyl (R)-(-)-3-Hydroxyisobutyrate;569FQ3X7KG;Methyl (R)-3-hydroxyisobutanoate;(R)-(-)-3-Hydroxyisobutyric Acid Methyl Ester;(R)-3-hydroxy-2-methylpropionic acid methyl ester;(2R)-3-Hydroxy-2-methylpropionic Acid Methyl Ester;methyl (R)-3-hydroxy-2-methylpropanoate;Methyl (2R)-3-hydroxy-2-methylpropionate;Propanoic acid, 3-hydroxy-2-methyl-, methyl ester, (R)-;MFCD00063450;Methyl 3-hydroxy-2-methylpropanoate #;R-OH isobutyrate;(?)-Rocheester;Roche ester (R);S00357a;(-)-Methyl D-beta-hydroxyisobutyrate;UNII-569FQ3X7KG;SCHEMBL765886;(R)-3-Hydroxy-2-methyl-propionic acid methyl ester;DTXSID90993497;(-)-Methyl beta-hydroxyisobutyrate;Methyl (R)-beta-hydroxyisobutyrate;AMY14231;AKOS015850839;AKOS015998824;(R)-Methyl3-hydroxy-2-methylpropanoate;AC-31278;DS-18187;CS-0019967;H0703;METHYL (R)-.BETA.-HYDROXYISOBUTYRATE;(-)-METHYL .BETA.-HYDROXYISOBUTYRATE;(R)-(-)-methyl-3-hydroxy-2-methylpropanoate;EN300-122792;F12962;Methyl (R)-(-)-3-hydroxy-2-methyl-propionate;A837584;Methyl (R)-(-)-3-Hydroxyisobutyrate, 99+ Percent;Methyl (R)-(-)-3-hydroxy-2-methylpropionate, 99%;?(R)-(-)-3-HYDROXY-2-METHYLPROPIONIC ACID METHYL ESTER

Suppliers and Price of (R)-Methyl 3-hydroxy-2-methylpropanoate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-3-HydroxyisobutyricAcidMethylEster
2g
$ 65.00

TCI Chemical
Methyl (R)-(-)-3-Hydroxyisobutyrate >99.0%(GC)
5g
$ 138.00

TCI Chemical
Methyl (R)-(-)-3-Hydroxyisobutyrate >99.0%(GC)
25g
$ 467.00

Sigma-Aldrich
Methyl (R)-(?)-3-hydroxy-2-methylpropionate 99%
5g
$ 153.00

Sigma-Aldrich
Methyl (R)-(?)-3-hydroxy-2-methylpropionate 99%
1g
$ 45.60

Frontier Specialty Chemicals
(R)-(-)-3-Hydroxy-2-methylpropionicacidmethylester 98%
5g
$ 190.00

Frontier Specialty Chemicals
(R)-(-)-3-Hydroxy-2-methylpropionicacidmethylester 98%
1g
$ 48.00

Chem-Impex
Methyl(R)-(-)-3-hydroxy-2-methylpropionate,99%(Chiralpurity) 99%(Chiralpurity)
1G
$ 40.32

Chem-Impex
Methyl(R)-(-)-3-hydroxy-2-methylpropionate,≥99%(Chiralpurity)Hazmat ≥99%(Chiralpurity)
5G
$ 154.92

American Custom Chemicals Corporation
(R)-(-)-3-HYDROXY-2-METHYLPROPIONIC ACID METHYL ESTER 95.00%
10G
$ 1382.48

Total 96 raw suppliers

Chemical Property of (R)-Methyl 3-hydroxy-2-methylpropanoate Edit

Chemical Property:

Appearance/Colour:Clear Colorless Oil
Vapor Pressure:0.361mmHg at 25°C
Refractive Index:n20/D 1.425
Boiling Point:76-77 °C12 mm Hg(lit.)
PKA:14.40±0.10(Predicted)
Flash Point:80 ºC
PSA：46.53000
Density:1.066
LogP:-0.21220
Storage Temp.:2-8°C
Solubility.:Chloroform (Sparingly), Methanol (Slightly)
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:118.062994177
Heavy Atom Count:8
Complexity:79.7

Purity/Quality:: (R)-3-HydroxyisobutyricAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s): R10:;
Hazard Codes:R10:;
Statements: 10
Safety Statements: 16

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CO)C(=O)OC
Isomeric SMILES:C[C@H](CO)C(=O)OC
Uses Chiral derivative of 3-Hydroxyisobutyrate. The (R)- and (S)-isomers are bifunctional building blocks for the synthesis of a wide variety of optically active molecules. Chiral derivative of 3-Hydroxyisobutyrate

Technology Process of (R)-Methyl 3-hydroxy-2-methylpropanoate

There total 10 articles about (R)-Methyl 3-hydroxy-2-methylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%