4-[4-(1-benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid

Base Information

Chemical Name:4-[4-(1-benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid
CAS No.:1267583-91-4
Molecular Formula:C₂₄H₂₈N₂O₃
Molecular Weight:392.498
Hs Code.:

Synonyms:4-[4-(1-benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid

Suppliers and Price of 4-[4-(1-benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[4-(1-benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[4-(1-benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid

There total 2 articles about 4-[4-(1-benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 2-[4-(3-Carboxy-propyl)-benzyl]-4-methyl-3-oxo-pentanoic acid ethyl ester

: 20570-96-1
benzylhydrazine dihydrochloride

: 1267583-91-4
4-[4-(1-benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid

Guidance literature:: benzylhydrazine dihydrochloride; With acetic acid; sodium hydroxide; In water;

2-[4-(3-Carboxy-propyl)-benzyl]-4-methyl-3-oxo-pentanoic acid ethyl ester; In water; for 4h; Reflux;

Reference yield:

: 135638-64-1
2-(1-hydroxy-2-methylpropyl)acrylic acid ethyl ester

: 1267583-91-4
4-[4-(1-benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium nitrite; tetrafluorohydroboric acid / water / -3 - 0.5 °C

1.2: 1.5 h / 6 - 65 °C

2.1: sodium hydroxide; acetic acid / water

2.2: 4 h / Reflux

With acetic acid; sodium hydroxide; tetrafluorohydroboric acid; sodium nitrite; In water;

Reference yield: 100.0%

: 64-17-5
ethanol

: 1267583-91-4
4-[4-(1-benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid

: 1267583-92-5
4-[4-(-Benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid ethyl ester

Guidance literature:: ethanol; With acetyl chloride; for 0.166667h; Cooling with water bath;

4-[4-(1-benzyl-5-hydroxy-3-isopropyl-1H-pyrazol-4-ylmethyl)-phenyl]-butyric acid; at 20 ℃; for 4h;