C₂₁H₁₅ClO₅

Base Information

• Chemical Name: C₂₁H₁₅ClO₅
• CAS No.: 1448310-42-6
• Molecular Formula: C₂₁H₁₅ClO₅
• Molecular Weight: 382.8
• Mol file: 1448310-42-6.mol

Synonyms:C₂₁H₁₅ClO₅

Chemical Property of C₂₁H₁₅ClO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₁₅ClO₅

There total 3 articles about C₂₁H₁₅ClO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,7-dichlorofluorescein (18362-80-6) → C21H15ClO5 (1448310-42-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydroxide / water / 1 h / 165 °C

2.1: sulfuric acid / 1.5 h / 0 - 90 °C

3.1: trichlorophosphate / 0.5 h / 0 °C

3.2: 3 h / 90 °C

With sulfuric acid; sodium hydroxide; trichlorophosphate; In water; 3.1: |Vilsmeier Reaction / 3.2: |Vilsmeier Reaction;

DOI:10.1002/chem.201300418

Reference yield:

C20H15ClO4 (1448310-41-5) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → C21H15ClO5 (1448310-42-6)

Guidance literature:

N,N-dimethyl-formamide; With trichlorophosphate; at 0 ℃; for 0.5h;

C₂₀H₁₅ClO₄; at 90 ℃; for 3h;

DOI:10.1002/chem.201300418

Reference yield:

2'-Carboxy-5-chloro-2,4-dihydroxybenzophenone (2513-23-7) → C21H15ClO5 (1448310-42-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sulfuric acid / 1.5 h / 0 - 90 °C

2.1: trichlorophosphate / 0.5 h / 0 °C

2.2: 3 h / 90 °C

With sulfuric acid; trichlorophosphate; 2.1: |Vilsmeier Reaction / 2.2: |Vilsmeier Reaction;

DOI:10.1002/chem.201300418

upstream raw materials:

C₂₀H₁₅ClO₄

N,N-dimethyl-formamide

2,7-dichlorofluorescein

2'-Carboxy-5-chloro-2,4-dihydroxybenzophenone

Downstream raw materials:

2-(3-(acryloyloxy)-2-chloro-5-(2,2-dicyanovinyl)-7,8-dihydro-6H-xanthen-9-yl)benzoic acid

2-(2-chloro-5-(2,2-dicyanovinyl)-3-hydroxy-7,8-dihydro-6H-xanthen-9-yl)benzoic acid

2-(2-chloro-5-(2-cyano-3-ethoxy-3-oxoprop-1-enyl)-3-hydroxy-7,8-dihydro-6H-xanthen-9-yl)benzoic acid

C₃₃H₂₉ClNO₄⁽¹⁺⁾*I^(1-)