2,3-Dichloro-5-nitro-1,4-naphthoquinone

Base Information

• Chemical Name: 2,3-Dichloro-5-nitro-1,4-naphthoquinone
• CAS No.: 22360-86-7
• Molecular Formula: C10H3Cl2NO4
• Molecular Weight: 272.044
• Hs Code.: 2914700090
• European Community (EC) Number: 634-516-8
• DSSTox Substance ID: DTXSID10402657
• Nikkaji Number: J510.016J
• Wikidata: Q82206098
• Mol file: 22360-86-7.mol

Synonyms:2,3-Dichloro-5-nitro-1,4-naphthoquinone;22360-86-7;2,3-dichloro-5-nitronaphthalene-1,4-dione;2,3-dichloro-5-nitronaphthoquinone;2,3-dichloro-5-nitro-1,4-dihydronaphthalene-1,4-dione;1,4-Naphthalenedione,2,3-dichloro-5-nitro-;SCHEMBL1393393;DTXSID10402657;XAA36086;MFCD00192929;AKOS001593464;AS-64986;CS-0205298;D2428;1,4-Naphthalenedione, 2,3-dichloro-5-nitro-;T70590;EN300-7381690;2,3-dichloro-1,4-dihydro-1,4-dioxo-5-nitronaphthalene;Z2574926058

Chemical Property of 2,3-Dichloro-5-nitro-1,4-naphthoquinone

Chemical Property:

• Melting Point: 176 °C
• Boiling Point: 400.2 °C at 760 mmHg
• Flash Point: 195.9 °C
• PSA: 79.96000
• Density: 1.71 g/cm³
• LogP: 3.18620
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 270.9439130
• Heavy Atom Count: 17
• Complexity: 440

Purity/Quality:

97% ^*data from raw suppliers

2,3-Dichloro-5-nitro-1,4-naphthoquinone ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)[N+](=O)[O-])C(=O)C(=C(C2=O)Cl)Cl

Technology Process of 2,3-Dichloro-5-nitro-1,4-naphthoquinone

There total 11 articles about 2,3-Dichloro-5-nitro-1,4-naphthoquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2,3-Dichloro-1,4-naphthoquinone (117-80-6) → 2,3-dichloro-5-nitro-1,4-naphthoquinone (22360-86-7) + 2,3-dichloro-6-nitronaphthalene-1,4-dione (29284-76-2)

Guidance literature:

With sulfuric acid; nitric acid; at 70 ℃; for 3h;

DOI:10.1021/jacs.7b07378

Reference yield:

2,3-Dichloro-1,4-naphthoquinone (117-80-6) → 2,3-dichloro-5-nitro-1,4-naphthoquinone (22360-86-7)

Guidance literature:

With sulfuric acid; nitric acid;

Reference yield:

5-nitro-1,4-naphthoquinone (17788-47-5) → 2,3-dichloro-5-nitro-1,4-naphthoquinone (22360-86-7)

Guidance literature:

With iodine; chlorine; In acetic acid; Heating;

DOI:10.1021/jm00158a031

upstream raw materials:

2,3-Dichloro-1,4-naphthoquinone

2,3,4-trichloro-4,5-dinitro-4H-naphthalen-1-one

acetic acid

5-nitro-1,4-naphthoquinone

Downstream raw materials:

2-amino-3-chloro-8-nitro-1,4-naphthoquinone

2-amino-3-chloro-5-nitro-1,4-naphthoquinone

2-anilino-3-chloro-8-nitro-1,4-naphthoquinone

2-anilino-3-chloro-5-nitro-1,4-naphthoquinone