5-(3-(4-fluorophenyl)-7-(5-((2-methoxyphenylsulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid

Base Information

Chemical Name:5-(3-(4-fluorophenyl)-7-(5-((2-methoxyphenylsulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid
CAS No.:1373275-28-5
Molecular Formula:C₃₀H₂₇FN₄O₇S
Molecular Weight:606.631
Hs Code.:

Synonyms:5-(3-(4-fluorophenyl)-7-(5-((2-methoxyphenylsulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid

Suppliers and Price of 5-(3-(4-fluorophenyl)-7-(5-((2-methoxyphenylsulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 5-(3-(4-fluorophenyl)-7-(5-((2-methoxyphenylsulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(3-(4-fluorophenyl)-7-(5-((2-methoxyphenylsulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid

There total 3 articles about 5-(3-(4-fluorophenyl)-7-(5-((2-methoxyphenylsulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.3%

: 1373278-80-8
methyl 5-(3-(4-fluorophenyl)-7-(5-((2-methoxy)phenyl(sulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

: 1373275-28-5
5-(3-(4-fluorophenyl)-7-(5-((2-methoxyphenylsulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 1373278-78-4
methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

: 1373275-28-5
5-(3-(4-fluorophenyl)-7-(5-((2-methoxyphenylsulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

2: pyridine / dichloromethane / 20 °C

3: water; lithium hydroxide / tetrahydrofuran / 20 °C

With pyridine; water; trifluoroacetic acid; lithium hydroxide; In tetrahydrofuran; dichloromethane;

Reference yield:

: 1373278-79-5
methyl 5-(7-(5-(aminomethyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

: 1373275-28-5
5-(3-(4-fluorophenyl)-7-(5-((2-methoxyphenylsulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 20 °C

2: water; lithium hydroxide / tetrahydrofuran / 20 °C

With pyridine; water; lithium hydroxide; In tetrahydrofuran; dichloromethane;