methyl 5-(3-(4-fluorophenyl)-7-(5-((2-methoxy)phenyl(sulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Base Information

Chemical Name:methyl 5-(3-(4-fluorophenyl)-7-(5-((2-methoxy)phenyl(sulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate
CAS No.:1373278-80-8
Molecular Formula:C₃₁H₂₉FN₄O₇S
Molecular Weight:620.658
Hs Code.:

Synonyms:methyl 5-(3-(4-fluorophenyl)-7-(5-((2-methoxy)phenyl(sulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 5-(3-(4-fluorophenyl)-7-(5-((2-methoxy)phenyl(sulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of methyl 5-(3-(4-fluorophenyl)-7-(5-((2-methoxy)phenyl(sulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

There total 2 articles about methyl 5-(3-(4-fluorophenyl)-7-(5-((2-methoxy)phenyl(sulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 10130-87-7
o-Methoxybenzenesulfonyl chloride

: 1373278-79-5
methyl 5-(7-(5-(aminomethyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

: 1373278-80-8
methyl 5-(3-(4-fluorophenyl)-7-(5-((2-methoxy)phenyl(sulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃;

Reference yield:

: 1373278-78-4
methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

: 1373278-80-8
methyl 5-(3-(4-fluorophenyl)-7-(5-((2-methoxy)phenyl(sulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

2: pyridine / dichloromethane / 20 °C

With pyridine; trifluoroacetic acid; In dichloromethane;