methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Base Information

Chemical Name:methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate
CAS No.:1373278-78-4
Molecular Formula:C₂₉H₃₁FN₄O₆
Molecular Weight:550.587
Hs Code.:

Synonyms:methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Suppliers and Price of methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

There total 1 articles about methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1373278-67-1
methyl 5-(3-(4-fluorophenyl)-7-((hydroxyimino)methyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

: 85363-04-8
tert-butyl cyanomethylcarbamate

: 1373278-78-4
methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Guidance literature:: With sodium hypochlorite; In dichloromethane; at 20 ℃;

Reference yield:

: 1373278-78-4
methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

: 1373278-79-5
methyl 5-(7-(5-(aminomethyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;

Reference yield:

: 1373278-78-4
methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

: 1373278-80-8
methyl 5-(3-(4-fluorophenyl)-7-(5-((2-methoxy)phenyl(sulfonamido)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

2: pyridine / dichloromethane / 20 °C

With pyridine; trifluoroacetic acid; In dichloromethane;