(3S,5S,7S)-7-{[tert-butyl(diphenyl)silyl]oxy}-5-methoxy-3-methyldecanal

Base Information

• Chemical Name: (3S,5S,7S)-7-{[tert-butyl(diphenyl)silyl]oxy}-5-methoxy-3-methyldecanal
• CAS No.: 1017238-09-3
• Molecular Formula: C₂₈H₄₂O₃Si
• Molecular Weight: 454.725
• Mol file: 1017238-09-3.mol

Synonyms:(3S,5S,7S)-7-{[tert-butyl(diphenyl)silyl]oxy}-5-methoxy-3-methyldecanal

Chemical Property of (3S,5S,7S)-7-{[tert-butyl(diphenyl)silyl]oxy}-5-methoxy-3-methyldecanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3S,5S,7S)-7-{[tert-butyl(diphenyl)silyl]oxy}-5-methoxy-3-methyldecanal

There total 9 articles about (3S,5S,7S)-7-{[tert-butyl(diphenyl)silyl]oxy}-5-methoxy-3-methyldecanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

S-ethyl (3S,5S,7S)-7-{[tert-butyl(diphenyl)silyl]oxy}-5-methoxy-3-methyldecanethioate (1017238-08-2) → (3S,5S,7S)-7-{[tert-butyl(diphenyl)silyl]oxy}-5-methoxy-3-methyldecanal (1017238-09-3)

Guidance literature:

With triethylsilane; 10% Pd/C; In dichloromethane; at 20 ℃; for 30h; Inert atmosphere;

DOI:10.1021/ol8001255

Reference yield: 93.0%

(3R,5S,7S)-7-(tert-butyldiphenylsilyloxy)-5-methoxy-3-methyldecan-1-ol → (3S,5S,7S)-7-{[tert-butyl(diphenyl)silyl]oxy}-5-methoxy-3-methyldecanal (1017238-09-3)

Guidance literature:

With sodium hydrogencarbonate; Dess-Martin periodane; In dichloromethane; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.tet.2009.11.054

Reference yield: 92.0%

C30H47NO4Si → (3S,5S,7S)-7-{[tert-butyl(diphenyl)silyl]oxy}-5-methoxy-3-methyldecanal (1017238-09-3)

Guidance literature:

With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 - 0 ℃; for 2h;

DOI:10.1016/j.tetlet.2018.12.066

upstream raw materials:

S-ethyl (3S,5S,7S)-7-{[tert-butyl(diphenyl)silyl]oxy}-5-methoxy-3-methyldecanethioate