3-(2-benzyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzoyl chloride

Base Information

Chemical Name:3-(2-benzyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzoyl chloride
CAS No.:1070292-57-7
Molecular Formula:C₂₄H₁₈ClNO₂
Molecular Weight:387.865
Hs Code.:

Synonyms:3-(2-benzyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzoyl chloride

Suppliers and Price of 3-(2-benzyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(2-benzyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzoyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(2-benzyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzoyl chloride

There total 5 articles about 3-(2-benzyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1070292-56-6
3-(2-benzyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzoic acid

: 1070292-57-7
3-(2-benzyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzoyl chloride

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 12h;

Reference yield:

: 876189-18-3
[5-(methoxycarbonyl)-2-methylphenyl]boronic acid

: 1070292-57-7
3-(2-benzyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzoyl chloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 12 h / 95 °C

2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C

2.2: 12 h / 20 °C

3.1: lithium hydroxide; water / methanol / 3 h / 20 - 50 °C

4.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 12 h / 20 °C

With lithium hydroxide; oxalyl dichloride; water; sodium hydride; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; N,N-dimethyl-formamide; In methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1070292-54-4
4-methyl-3-(1-oxo-1,2-dihydroisoquinolin-6-yl)benzoic acid methyl ester

: 1070292-57-7
3-(2-benzyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzoyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C

1.2: 12 h / 20 °C

2.1: lithium hydroxide; water / methanol / 3 h / 20 - 50 °C

3.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 12 h / 20 °C

With lithium hydroxide; oxalyl dichloride; water; sodium hydride; N,N-dimethyl-formamide; In methanol; dichloromethane; N,N-dimethyl-formamide;