α-<(phenylmethyl)amino>-2-naphthalenacetonitrile

Base Information

Chemical Name:α-<(phenylmethyl)amino>-2-naphthalenacetonitrile
CAS No.:69243-87-4
Molecular Formula:C₁₉H₁₆N₂
Molecular Weight:272.349
Hs Code.:

Synonyms:α-<(phenylmethyl)amino>-2-naphthalenacetonitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of α-<(phenylmethyl)amino>-2-naphthalenacetonitrile

Chemical Property:

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Technology Process of α-<(phenylmethyl)amino>-2-naphthalenacetonitrile

There total 2 articles about α-<(phenylmethyl)amino>-2-naphthalenacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 74-90-8
hydrogen cyanide

: 141120-50-5
(E)-N-benzyl-1-(naphthalen-2-yl)methanimine

: 69243-87-4
α-<(phenylmethyl)amino>-2-naphthalenacetonitrile

Guidance literature:: With Sc[(R)-BINOL]2Li; In toluene; at -20 ℃; for 1h;
DOI:10.1016/S0957-4166(01)00144-6

Reference yield: 45.0%

: 7677-24-9
trimethylsilyl cyanide

: 141120-50-5
(E)-N-benzyl-1-(naphthalen-2-yl)methanimine

: 69243-87-4
α-<(phenylmethyl)amino>-2-naphthalenacetonitrile

Guidance literature:: With Sc[(R)-BINOL]2Li; In toluene; at -20 ℃; for 3h;
DOI:10.1016/S0957-4166(01)00144-6

Reference yield: 90.0%

: 1242071-55-1
methyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate

: 69243-87-4
α-<(phenylmethyl)amino>-2-naphthalenacetonitrile

: 1404296-12-3
methyl 2-({benzyl[cyano(naphthalen-2-yl)methyl]amino}methyl)acrylate

Guidance literature:: With 1,4-diaza-bicyclo[2.2.2]octane; In toluene; at 30 ℃; for 3h; regioselective reaction; Inert atmosphere; Molecular sieve;
DOI:10.1002/ejoc.201200642