N-tert-butyloxycarbonyl-protected 2-[4-[[2-(trifluoromethyl)-4-pyridyl]oxy]phenyl]ethanamine

Base Information

Chemical Name:N-tert-butyloxycarbonyl-protected 2-[4-[[2-(trifluoromethyl)-4-pyridyl]oxy]phenyl]ethanamine
CAS No.:1313399-63-1
Molecular Formula:C₁₉H₂₁F₃N₂O₃
Molecular Weight:382.383
Hs Code.:

Synonyms:N-tert-butyloxycarbonyl-protected 2-[4-[[2-(trifluoromethyl)-4-pyridyl]oxy]phenyl]ethanamine

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Chemical Property of N-tert-butyloxycarbonyl-protected 2-[4-[[2-(trifluoromethyl)-4-pyridyl]oxy]phenyl]ethanamine

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Technology Process of N-tert-butyloxycarbonyl-protected 2-[4-[[2-(trifluoromethyl)-4-pyridyl]oxy]phenyl]ethanamine

There total 4 articles about N-tert-butyloxycarbonyl-protected 2-[4-[[2-(trifluoromethyl)-4-pyridyl]oxy]phenyl]ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 64318-28-1
N-t-butoxycarbonyl-tyramine

: 131748-14-6
4-chloro-2-trifluoromethylpyridine

: 1313399-63-1
N-tert-butyloxycarbonyl-protected 2-[4-[[2-(trifluoromethyl)-4-pyridyl]oxy]phenyl]ethanamine

Guidance literature:: N-t-butoxycarbonyl-tyramine; With potassium carbonate; potassium iodide; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 0.166667h;

4-chloro-2-trifluoromethylpyridine; In 1-methyl-pyrrolidin-2-one; at 160 ℃; for 6h;

Reference yield: 48.0%

: 1448545-44-5
2-(2-fluoro-4-hydroxyphenyl)ethylamine-tert-butyl carbamate

: 131748-14-6
4-chloro-2-trifluoromethylpyridine

: 1313399-63-1
N-tert-butyloxycarbonyl-protected 2-[4-[[2-(trifluoromethyl)-4-pyridyl]oxy]phenyl]ethanamine

Guidance literature:: 2-(2-fluoro-4-hydroxyphenyl)ethylamine-tert-butyl carbamate; With potassium carbonate; potassium iodide; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 0.166667h;

4-chloro-2-trifluoromethylpyridine; In 1-methyl-pyrrolidin-2-one; at 160 ℃; for 6h;