C₁₇H₂₂O₃S

Base Information

• Chemical Name: C₁₇H₂₂O₃S
• CAS No.: 1001327-35-0
• Molecular Formula: C₁₇H₂₂O₃S
• Molecular Weight: 306.426
• Mol file: 1001327-35-0.mol

Synonyms:C₁₇H₂₂O₃S

Chemical Property of C₁₇H₂₂O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of C₁₇H₂₂O₃S

There total 3 articles about C₁₇H₂₂O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C27H35NO3S → C17H22O3S (1001327-35-0)

Guidance literature:

With sulfuric acid; water; In 1,4-dioxane; at 110 ℃; for 18h; Heating / reflux;

Reference yield:

(E)-2-(4-(cyclopropylthio)phenyl)-3-(tetrahydro-2H-pyran-4-yl)acrylic acid (1207106-17-9) → C17H22O3S (1001327-35-0)

Guidance literature:

With C₃₂H₁₂BF₂₄^(1-)*C₄₀H₄₄IrNOP⁽¹⁺⁾; hydrogen; triethylamine; In methanol; at 30 - 50 ℃; for 20h; under 22801.5 Torr; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1039/b919902k

Reference yield:

(3R)-(-4,4-dimethyl-2-oxotetrahydrofuran-3-yl) 2-(4-(cyclopropylthio)phenyl)-3-(tetrahydro-2H-pyran-4-yl)propanoate → C17H22O3S (1001327-35-0) + C17H22O3S

Guidance literature:

With sodium hydroxide; lithium hydroxide; In tetrahydrofuran; water; at 0 ℃;

DOI:10.1021/op300139g

upstream raw materials:

(E)-2-(4-(cyclopropylthio)phenyl)-3-(tetrahydro-2H-pyran-4-yl)acrylic acid

Downstream raw materials:

(R)-2-(4-(cyclopropylsulfonyl)phenyl)-3-(tetrahydro-2H-pyran-4-yl)propanoic acid

Refernces

• 1、 Zhang, Yi,Han, Zhaobin,Li, Fuying,Ding, Kuiling,Zhang, Ao. "Highly enantioselective hydrogenation of α-aryl-β-substituted acrylic acids catalyzed by Ir-SpinPHOX". supporting information; experimental part. p. 156 - 158. Retrieved 2010/04/02.
• 2、 -. "NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME". Page/Page column 65. . Retrieved 2008/06/13.