3-(p-chlorophenyl)glutaramide

Base Information

• Chemical Name: 3-(p-chlorophenyl)glutaramide
• CAS No.: 159156-84-0
• Molecular Formula: C₁₁H₁₂ClNO₃
• Molecular Weight: 241.674
• Mol file: 159156-84-0.mol

Synonyms:3-(p-chlorophenyl)glutaramide

Chemical Property of 3-(p-chlorophenyl)glutaramide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 3-(p-chlorophenyl)glutaramide

There total 11 articles about 3-(p-chlorophenyl)glutaramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(R)-3-(4-chlorophenyl)-glutaric acid monomethyl ester (137310-16-8) → 3-(p-chlorophenyl)glutaramide (159156-84-0)

Guidance literature:

With ammonia; In methanol; at 40 ℃; for 48h;

DOI:10.1139/v94-294

Reference yield:

3-(p-chlorophenyl)-glutaramide → 3-(p-chlorophenyl)glutaramide (159156-84-0)

Guidance literature:

Delftia acidovorans NBRC₁₃₅₈₂; at 30 ℃; for 24h; pH=7; Product distribution / selectivity; Phosphate buffer; Microbiological reaction;

Reference yield:

3-(4-chlorophenyl)pentane-1,5-dioic acid (35271-74-0) → 3-(p-chlorophenyl)glutaramide (159156-84-0)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / 2 h

2: ammonia / methanol / 72 h

3: Delftia acidovorans NBRC₁₃₅₈₂ / 24 h / 30 °C / pH 7 / Phosphate buffer; Microbiological reaction

With thionyl chloride; ammonia; Delftia acidovorans NBRC₁₃₅₈₂; In methanol;

upstream raw materials:

(R)-3-(4-chlorophenyl)-glutaric acid monomethyl ester

3-(4-chlorophenyl)prop-2-enoic acid

methyl 3-(4-chlorophenyl)propenoate

dimethyl 3-(p-chlorophenyl)glutarate