6'-PNZ-2'-guanidinium-3,3''-diBoc-1-(N-Boc-4-amino-2(S)-hydroxy-butyryl)-sisomicin

Base Information

Chemical Name:6'-PNZ-2'-guanidinium-3,3''-diBoc-1-(N-Boc-4-amino-2(S)-hydroxy-butyryl)-sisomicin
CAS No.:1154760-97-0
Molecular Formula:C₄₇H₇₅N₉O₁₉
Molecular Weight:1070.16
Hs Code.:

Synonyms:6'-PNZ-2'-guanidinium-3,3''-diBoc-1-(N-Boc-4-amino-2(S)-hydroxy-butyryl)-sisomicin

Suppliers and Price of 6'-PNZ-2'-guanidinium-3,3''-diBoc-1-(N-Boc-4-amino-2(S)-hydroxy-butyryl)-sisomicin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6'-PNZ-2'-guanidinium-3,3''-diBoc-1-(N-Boc-4-amino-2(S)-hydroxy-butyryl)-sisomicin

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6'-PNZ-2'-guanidinium-3,3''-diBoc-1-(N-Boc-4-amino-2(S)-hydroxy-butyryl)-sisomicin

There total 11 articles about 6'-PNZ-2'-guanidinium-3,3''-diBoc-1-(N-Boc-4-amino-2(S)-hydroxy-butyryl)-sisomicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1154758-71-0
6',2'-diPNZ-3,3''-diBoc-1-(N-Boc-4-amino-2(S)-hydroxy-butyryl)-sisomicin

: 4023-02-3
1H-pyrazole-1-carboximidamide hydrochloride

: 1154760-97-0
6'-PNZ-2'-guanidinium-3,3''-diBoc-1-(N-Boc-4-amino-2(S)-hydroxy-butyryl)-sisomicin

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 80 ℃;

Reference yield:

: 6',2'-diPNZ-sisomicin

: 1154760-97-0
6'-PNZ-2'-guanidinium-3,3''-diBoc-1-(N-Boc-4-amino-2(S)-hydroxy-butyryl)-sisomicin

Guidance literature:: Multi-step reaction with 6 steps

1.1: zinc diacetate / methanol / 20 °C / Cooling with ice

2.1: N,N-dimethyl-formamide / 0.5 h / -40 °C

2.2: 3 h / -40 °C

3.1: 4-methyl-morpholine / tetrahydrofuran / 18 h / 0 °C

4.1: sodium dithionite; water; sodium hydroxide / ethanol / 18 h / 70 °C

5.1: N-ethyl-N,N-diisopropylamine / methanol / 1 h

6.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 80 °C

With 4-methyl-morpholine; sodium dithionite; zinc diacetate; water; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; N,N-dimethyl-formamide;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1154760-97-0
6'-PNZ-2'-guanidinium-3,3''-diBoc-1-(N-Boc-4-amino-2(S)-hydroxy-butyryl)-sisomicin

Guidance literature:: Multi-step reaction with 6 steps

1.1: potassium carbonate / 1,4-dioxane; water

2.1: N,N-dimethyl-formamide / 0.5 h / -40 °C

2.2: 3 h / -40 °C

3.1: 4-methyl-morpholine / tetrahydrofuran / 18 h / 0 °C

4.1: sodium dithionite; water; sodium hydroxide / ethanol / 18 h / 70 °C

5.1: N-ethyl-N,N-diisopropylamine / methanol / 1 h

6.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 80 °C

With 4-methyl-morpholine; sodium dithionite; water; potassium carbonate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; methanol; ethanol; water; N,N-dimethyl-formamide;