p-MPPF

Base Information

Chemical Name:p-MPPF
CAS No.:155204-26-5
Molecular Formula:C25H27 F N4 O2
Molecular Weight:434.513
Hs Code.:2933990090
UNII:81KHI46E5L
DSSTox Substance ID:DTXSID20424966
Nikkaji Number:J621.990J
Wikipedia:MPPF
Wikidata:Q427094
Pharos Ligand ID:QYDU2L43MQYS
ChEMBL ID:CHEMBL286607
Mol file:155204-26-5.mol

Synonyms:4-(2' methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-fluorobenzamido)ethyl)piperazine;4-MPPF;p-MPPF

Suppliers and Price of p-MPPF

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-FLUORO-N-[2-[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL]ETHYL]-N-PYRIDIN-2-YLBENZAMIDE 95.00%
10MG
$ 975.00

American Custom Chemicals Corporation
4-FLUORO-N-[2-[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL]ETHYL]-N-PYRIDIN-2-YLBENZAMIDE 95.00%
5MG
$ 675.00

Total 2 raw suppliers

Chemical Property of p-MPPF

Chemical Property:

Appearance/Colour:white solid
Boiling Point:614.4 °C at 760 mmHg
Flash Point:325.4 °C
PSA：48.91000
Density:1.228 g/cm³
LogP:3.70120
Storage Temp.:2-8°C
Solubility.:ethanol: 15 mg/mL
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:434.21180428
Heavy Atom Count:32
Complexity:578

Purity/Quality:: 4-FLUORO-N-[2-[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL]ETHYL]-N-PYRIDIN-2-YLBENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4=CC=C(C=C4)F

Technology Process of p-MPPF

There total 12 articles about p-MPPF which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 403-43-0
4-fluorobenzoyl chloride

: 155204-28-7
1-(2-methoxyphenyl)-4-(2-(2-pyridylamino)ethyl)piperazine

: 155204-26-5
4-fluoro-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-pyridin-2-ylbenzylamide

Guidance literature:: With triethylamine; In acetonitrile;
DOI:10.1021/ja067276c

Reference yield: 65.0%

: C₂₅H₂₈N₄O₃

: 155204-26-5
4-fluoro-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-pyridin-2-ylbenzylamide

Guidance literature:: With fluorosulfonyl fluoride; tetramethylammonium fluoride; In N,N-dimethyl-formamide; at 100 ℃; for 24h; Inert atmosphere; Glovebox; Sealed tube;
DOI:10.1021/jacs.6b12911

Reference yield: 53.0%

: 155204-27-6
p-MPPN

: 155204-26-5
4-fluoro-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-pyridin-2-ylbenzylamide

Guidance literature:: With fluorosulfonyl fluoride; tetramethylammonium 2,6-dimethylphenoxide; In N,N-dimethyl-formamide; at 100 ℃; for 24h; Sealed tube;
DOI:10.1021/acs.joc.7b00481