2-AMINO-4-BROMOBENZONITRILE

Base Information

Chemical Name:2-AMINO-4-BROMOBENZONITRILE
CAS No.:304858-65-9
Molecular Formula:C7H5BrN2
Molecular Weight:197.034
Hs Code.:2926909090
European Community (EC) Number:807-525-1
DSSTox Substance ID:DTXSID90432816
Nikkaji Number:J1.378.757C
Wikidata:Q72438424
ChEMBL ID:CHEMBL4514868
Mol file:304858-65-9.mol

Synonyms:2-Amino-4-bromobenzonitrile;benzonitrile, 2-amino-4-bromo-;

Suppliers and Price of 2-AMINO-4-BROMOBENZONITRILE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-4-bromobenxonitrile
2.5g
$ 75.00

TRC
2-Amino-4-bromobenxonitrile
500mg
$ 60.00

SynQuest Laboratories
2-Amino-4-bromobenzonitrile
1 g
$ 16.00

Matrix Scientific
2-Amino-4-bromobenzonitrile 98%
25g
$ 47.00

Matrix Scientific
2-Amino-4-bromobenzonitrile 98%
5g
$ 15.00

Crysdot
2-Amino-4-bromobenzonitrile 98%
500g
$ 554.00

Biosynth Carbosynth
2-Amino-4-bromobenzonitrile
50 mg
$ 704.00

Biosynth Carbosynth
2-Amino-4-bromobenzonitrile
25 mg
$ 405.00

Biosynth Carbosynth
2-Amino-4-bromobenzonitrile
10 mg
$ 203.00

Biosynth Carbosynth
2-Amino-4-bromobenzonitrile
5 mg
$ 117.00

Total 49 raw suppliers

Chemical Property of 2-AMINO-4-BROMOBENZONITRILE

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.652
Boiling Point:317.825 °C at 760 mmHg
PKA:0.74±0.10(Predicted)
Flash Point:146.015 °C
PSA：49.81000
Density:1.69 g/cm³
LogP:2.48418
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:195.96361
Heavy Atom Count:10
Complexity:160

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-4-bromobenxonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Br)N)C#N
Uses 2-Amino-4-bromobenxonitrile can be used to synthesize IRAK4 inhibitors to treat autoimmune diseases or cancers.

Technology Process of 2-AMINO-4-BROMOBENZONITRILE

There total 7 articles about 2-AMINO-4-BROMOBENZONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1885-29-6
anthranilic acid nitrile

: 304858-65-9
2-amino-4-bromobenzonitrile

Guidance literature:: With N-Bromosuccinimide; lithium perchlorate; silica gel; In dichloromethane; at 20 ℃; for 0.0833333h;
DOI:10.1139/v05-001

Reference yield: 92.0%

: 79603-03-5
4-bromo-2-nitro-benzonitrile

: 304858-65-9
2-amino-4-bromobenzonitrile

Guidance literature:: With hydrogenchloride; tin(ll) chloride; In water; at 0 - 20 ℃; for 1h;

Reference yield: 82.0%

: 115049-55-3
6-bromo-3-(hydroxyimino)indolin-2-one

: 304858-65-9
2-amino-4-bromobenzonitrile

Guidance literature:: 6-bromo-3-(hydroxyimino)indolin-2-one; With 2,6-dimethylpyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 0 ℃; for 3h; Cooling with ice; Reflux;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 - 30 ℃; for 1h;
DOI:10.2174/15734064113096660046