3'-azido-3'-deoxythymidin-5'-yl 3-O-(4'-benzhydryloxy-3',3'-dimethylsuccinyl)-lup-2'⁽²⁹⁾en-28-yl 3,3-dimethylglutarate

Base Information

• Chemical Name: 3'-azido-3'-deoxythymidin-5'-yl 3-O-(4'-benzhydryloxy-3',3'-dimethylsuccinyl)-lup-2'⁽²⁹⁾en-28-yl 3,3-dimethylglutarate
• CAS No.: 1252258-63-1
• Molecular Formula: C₆₆H₈₉N₅O₁₁
• Molecular Weight: 1128.46

Synonyms:3'-azido-3'-deoxythymidin-5'-yl 3-O-(4'-benzhydryloxy-3',3'-dimethylsuccinyl)-lup-2'⁽²⁹⁾en-28-yl 3,3-dimethylglutarate

Chemical Property of 3'-azido-3'-deoxythymidin-5'-yl 3-O-(4'-benzhydryloxy-3',3'-dimethylsuccinyl)-lup-2'⁽²⁹⁾en-28-yl 3,3-dimethylglutarate

Chemical Property:

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Technology Process of 3'-azido-3'-deoxythymidin-5'-yl 3-O-(4'-benzhydryloxy-3',3'-dimethylsuccinyl)-lup-2'⁽²⁹⁾en-28-yl 3,3-dimethylglutarate

There total 1 articles about 3'-azido-3'-deoxythymidin-5'-yl 3-O-(4'-benzhydryloxy-3',3'-dimethylsuccinyl)-lup-2'⁽²⁹⁾en-28-yl 3,3-dimethylglutarate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.2%

3-O-(4'-benzhydryloxy-3',3'-dimethylsuccinyl)-28-O-(3'',3''-dimethylglutaryl)betulin (1252258-49-3) + 3'-azido-2',3'-deoxythymidine (30516-87-1,399024-19-2) → 3'-azido-3'-deoxythymidin-5'-yl 3-O-(4'-benzhydryloxy-3',3'-dimethylsuccinyl)-lup-2'(29)en-28-yl 3,3-dimethylglutarate (1252258-63-1)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃;

DOI:10.1016/j.bmc.2010.06.092

upstream raw materials:

3-O-(4'-benzhydryloxy-3',3'-dimethylsuccinyl)-28-O-(3'',3''-dimethylglutaryl)betulin

3'-azido-2',3'-deoxythymidine

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