Chloro-acetic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester

Base Information

Chemical Name:Chloro-acetic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester
CAS No.:745831-83-8
Molecular Formula:C₁₈H₁₈ClNO₄S
Molecular Weight:379.864
Hs Code.:

Synonyms:Chloro-acetic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester

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Chemical Property of Chloro-acetic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester

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Technology Process of Chloro-acetic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester

There total 1 articles about Chloro-acetic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 79-04-9
chloroacetyl chloride

: 175523-35-0
(+)-(1R,2S)-1-(N-tosylamino)-2-indanol

: 745831-83-8
Chloro-acetic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester

Guidance literature:: With pyridine; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1021/ol0490835

Reference yield: 94.0%

: 53346-05-7,41954-96-5,81445-44-5,81445-45-6
(R)-2-benzyloxypropanal

: 745831-83-8
Chloro-acetic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester

: 745832-02-4
(2R,3S,4R)-4-Benzyloxy-2-chloro-3-hydroxy-pentanoic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester

Guidance literature:: Chloro-acetic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester; With titanium tetrachloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃;

(R)-2-benzyloxypropanal; With titanium tetrachloride; In dichloromethane; at -78 ℃; for 0.0833333h;
DOI:10.1021/ol0490835

Reference yield: 90.0%

: 590-86-3
isovaleraldehyde

: 745831-83-8
Chloro-acetic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester

: 745831-94-1
(2R,3R)-2-Chloro-3-hydroxy-5-methyl-hexanoic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester

Guidance literature:: Chloro-acetic acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester; With titanium tetrachloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃;

isovaleraldehyde; With 1-methyl-pyrrolidin-2-one; titanium tetrachloride; In dichloromethane; at -78 ℃; for 0.0833333h;
DOI:10.1021/ol0490835