5-(4-methoxyphenyl)-3-(1-methylpiperidin-4-yl)-1-(triisopropylsilyl)-indole

Base Information

Chemical Name:5-(4-methoxyphenyl)-3-(1-methylpiperidin-4-yl)-1-(triisopropylsilyl)-indole
CAS No.:253439-70-2
Molecular Formula:C₃₀H₄₄N₂OSi
Molecular Weight:476.778
Hs Code.:

Synonyms:5-(4-methoxyphenyl)-3-(1-methylpiperidin-4-yl)-1-(triisopropylsilyl)-indole

Suppliers and Price of 5-(4-methoxyphenyl)-3-(1-methylpiperidin-4-yl)-1-(triisopropylsilyl)-indole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(4-methoxyphenyl)-3-(1-methylpiperidin-4-yl)-1-(triisopropylsilyl)-indole

Chemical Property:

Purity/Quality:

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Technology Process of 5-(4-methoxyphenyl)-3-(1-methylpiperidin-4-yl)-1-(triisopropylsilyl)-indole

There total 5 articles about 5-(4-methoxyphenyl)-3-(1-methylpiperidin-4-yl)-1-(triisopropylsilyl)-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

: 253436-67-8
5-bromo-3-(1-methylpiperidin-4-yl)-1-(triisopropylsilyl)-1H-indole

: 5720-07-0
4-methoxyphenylboronic acid

: 497-19-8
sodium carbonate

: 253439-70-2
5-(4-methoxyphenyl)-3-(1-methylpiperidin-4-yl)-1-(triisopropylsilyl)-indole

Guidance literature:: tetrakis(triphenylphosphine)palladium ⁽⁰⁾; In toluene;

Reference yield:

: 10075-50-0
5-bromo-1H-indole

: 253439-70-2
5-(4-methoxyphenyl)-3-(1-methylpiperidin-4-yl)-1-(triisopropylsilyl)-indole

Guidance literature:: Multi-step reaction with 4 steps

1: potassium hydroxide / methanol

2: tetrahydrofuran

3: tetrahydrofuran; dichloromethane; mineral oil

4: tetrakis(triphenylphosphine)palladium ⁽⁰⁾ / toluene

With potassium hydroxide; tetrakis(triphenylphosphine)palladium ⁽⁰⁾; In tetrahydrofuran; methanol; dichloromethane; toluene; mineral oil;

Reference yield:

: 1445-73-4
1-Methyl-4-piperidone

: 253439-70-2
5-(4-methoxyphenyl)-3-(1-methylpiperidin-4-yl)-1-(triisopropylsilyl)-indole

Guidance literature:: Multi-step reaction with 4 steps

1: potassium hydroxide / methanol

2: tetrahydrofuran

3: tetrahydrofuran; dichloromethane; mineral oil

4: tetrakis(triphenylphosphine)palladium ⁽⁰⁾ / toluene

With potassium hydroxide; tetrakis(triphenylphosphine)palladium ⁽⁰⁾; In tetrahydrofuran; methanol; dichloromethane; toluene; mineral oil;