N-benzyl-1-cyclohexyl-N-methylmethanamine

Base Information

• Chemical Name: N-benzyl-1-cyclohexyl-N-methylmethanamine
• CAS No.: 79952-95-7
• Molecular Formula: C₁₅H₂₃N
• Molecular Weight: 217.354
• Mol file: 79952-95-7.mol

Synonyms:N-benzyl-1-cyclohexyl-N-methylmethanamine

Chemical Property of N-benzyl-1-cyclohexyl-N-methylmethanamine

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of N-benzyl-1-cyclohexyl-N-methylmethanamine

There total 15 articles about N-benzyl-1-cyclohexyl-N-methylmethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

carbon monoxide (201230-82-2) + benzyl-methyl-amine (103-67-3) + cyclohexene (110-83-8) → N-benzyl-1-cyclohexyl-N-methylmethanamine (79952-95-7)

Guidance literature:

With 1-Methylpyrrolidine; water; 3>PF6; at 140 ℃; for 6h; under 51714.8 Torr;

DOI:10.1021/jo00342a013

Reference yield: 79.0%

benzyl-methyl-amine (103-67-3) + sodium cyclohexyl(hydroxyl)methanesulfonate → N-benzyl-1-cyclohexyl-N-methylmethanamine (79952-95-7)

Guidance literature:

sodium cyclohexyl(hydroxyl)methanesulfonate; With triethylamine; In 1,2-dichloro-ethane; at 20 ℃; for 0.25h; Inert atmosphere;

benzyl-methyl-amine; In 1,2-dichloro-ethane; at 20 ℃; for 0.75h; Inert atmosphere;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; for 16.5h; Inert atmosphere;

DOI:10.1055/s-0029-1217050

Reference yield: 78.0%

N-methyl-N-(butoxymethyl)benzylamine (39931-20-9) + cyclohexylmagnesiumchloride (931-51-1) → N-benzyl-1-cyclohexyl-N-methylmethanamine (79952-95-7)

Guidance literature:

DOI:10.1016/S0040-4039(00)70703-9

upstream raw materials:

N-benzyl-N-methylcyclohexanecarboxamide

N-methyl-N-(butoxymethyl)benzylamine

cyclohexylmagnesiumchloride

carbon monoxide