N'-(1-benzylpiperidin-4-yl)ethane-1,2-diamine

Base Information

Chemical Name:N'-(1-benzylpiperidin-4-yl)ethane-1,2-diamine
CAS No.:308362-93-8
Molecular Formula:C₁₄H₂₃N₃
Molecular Weight:233.357
Hs Code.:
DSSTox Substance ID:DTXSID201215719

Synonyms:N'-(1-benzylpiperidin-4-yl)ethane-1,2-diamine;308362-93-8;DTXSID201215719;AKOS006040056;N-(1-Benzylpiperidin-4-yl)ethane-1, 2-diamine;N1-[1-(Phenylmethyl)-4-piperidinyl]-1,2-ethanediamine

Suppliers and Price of N'-(1-benzylpiperidin-4-yl)ethane-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N'-(1-benzylpiperidin-4-yl)ethane-1,2-diamine

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:233.189197746
Heavy Atom Count:17
Complexity:194

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCC1NCCN)CC2=CC=CC=C2

Technology Process of N'-(1-benzylpiperidin-4-yl)ethane-1,2-diamine

There total 2 articles about N'-(1-benzylpiperidin-4-yl)ethane-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 280141-48-2
tert-butyl 2-(1-benzylpiperidin-4-ylamino)ethylcarbamate

: 308362-93-8
N₁-(1-benzylpiperidin-4-yl)ethane-1, 2-diamine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; for 2h;

Reference yield:

: 50541-93-0
4-amino-1-benzylpiperidine

: 308362-93-8
N₁-(1-benzylpiperidin-4-yl)ethane-1, 2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

With potassium carbonate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.03.049