2-(benzyloxy)-5-chloro-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)aniline

Base Information

Chemical Name:2-(benzyloxy)-5-chloro-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)aniline
CAS No.:1289486-06-1
Molecular Formula:C₂₆H₂₈ClNO₃
Molecular Weight:437.966
Hs Code.:

Synonyms:2-(benzyloxy)-5-chloro-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)aniline

Suppliers and Price of 2-(benzyloxy)-5-chloro-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(benzyloxy)-5-chloro-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)aniline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(benzyloxy)-5-chloro-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)aniline

There total 8 articles about 2-(benzyloxy)-5-chloro-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 6373-47-3
2-(benzyloxy)-5-chloroaniline

: 144800-91-9
4-(3-(bromomethyl)phenyl)-4-methoxytetrahydro-2H-pyran

: 1289486-06-1
2-(benzyloxy)-5-chloro-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)aniline

Guidance literature:: With potassium carbonate; In acetone; Reflux;
DOI:10.1016/j.bmc.2011.01.043

Reference yield:

: 29943-42-8,143562-54-3
Tetrahydro-4H-pyran-4-one

: 1289486-06-1
2-(benzyloxy)-5-chloro-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)aniline

Guidance literature:: Multi-step reaction with 4 steps

1.1: magnesium / tetrahydrofuran / Reflux

1.2: 1 h / Reflux

2.1: sodium hydride / tetrahydrofuran; mineral oil / 15 h / 20 °C

3.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 1.5 h / Reflux

4.1: potassium carbonate / acetone / Reflux

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); sodium hydride; potassium carbonate; magnesium; In tetrahydrofuran; tetrachloromethane; acetone; mineral oil;
DOI:10.1016/j.bmc.2011.01.043

Reference yield:

: 1289485-53-5
C₂₁H₁₄ClNO₃

: 1289486-06-1
2-(benzyloxy)-5-chloro-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: water; hydrazine / ethanol / 2 h / Reflux

2: potassium carbonate / acetone / Reflux

With water; potassium carbonate; hydrazine; In ethanol; acetone;
DOI:10.1016/j.bmc.2011.01.043