Dimethyl 4-hydroxy-5-methylphthalate

Base Information

Chemical Name:Dimethyl 4-hydroxy-5-methylphthalate
CAS No.:22481-13-6
Molecular Formula:C₁₁H₁₂O₅
Molecular Weight:224.213
Hs Code.:
DSSTox Substance ID:DTXSID001334430

Synonyms:dimethyl 4-hydroxy-5-methylphthalate;22481-13-6;dimethyl 4-hydroxy-5-methylbenzene-1,2-dicarboxylate;DTXSID001334430;dimethyl4-hydroxy-5-methylphthalate

Suppliers and Price of Dimethyl 4-hydroxy-5-methylphthalate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Dimethyl 4-hydroxy-5-methylphthalate

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:224.06847348
Heavy Atom Count:16
Complexity:276

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C=C1O)C(=O)OC)C(=O)OC

Technology Process of Dimethyl 4-hydroxy-5-methylphthalate

There total 5 articles about Dimethyl 4-hydroxy-5-methylphthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 116809-99-5
5-methyl-4-(2-bromoethoxy)-1,2-benzenedicarboxylic acid bis(methyl ester)

: 22481-13-6
5-methyl-4-hydroxy-1,2-benzenedicarboxylic acid bis(methyl ester)

Guidance literature:: With ammonium chloride; zinc; In ethanol; for 1h; Heating;
DOI:10.1021/jo00259a012

Reference yield:

: 116809-94-0
5-methyl-4-(2-hydroxyethoxy)-1,2-benzenedicarboxylic acid bis(methyl ester)

: 22481-13-6
5-methyl-4-hydroxy-1,2-benzenedicarboxylic acid bis(methyl ester)

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / Br₂, Ph₃P / acetonitrile

2: 88 percent / aq. NH₄Cl, Zn / ethanol / 1 h / Heating

With bromine; ammonium chloride; triphenylphosphine; zinc; In ethanol; acetonitrile;
DOI:10.1021/jo00259a012