4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-2-<<2-<(4-chloropyrimid-6-yl)amino>ethoxy>methyl>-1,4-dihydropyridine

Base Information

• Chemical Name: 4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-2-<<2-<(4-chloropyrimid-6-yl)amino>ethoxy>methyl>-1,4-dihydropyridine
• CAS No.: 93117-91-0
• Molecular Formula: C₂₄H₂₅Cl₃N₄O₅
• Molecular Weight: 555.845
• Mol file: 93117-91-0.mol

Synonyms:4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-2-<<2-<(4-chloropyrimid-6-yl)amino>ethoxy>methyl>-1,4-dihydropyridine

Chemical Property of 4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-2-<<2-<(4-chloropyrimid-6-yl)amino>ethoxy>methyl>-1,4-dihydropyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-2-<<2-<(4-chloropyrimid-6-yl)amino>ethoxy>methyl>-1,4-dihydropyridine

There total 1 articles about 4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-2-<<2-<(4-chloropyrimid-6-yl)amino>ethoxy>methyl>-1,4-dihydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

4,6-dichloropyrimidine (1193-21-1) + 2-[(2-aminoethoxy)methyl]-4-(2,3-dichlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine (88150-50-9) → 4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-2-<<2-<(4-chloropyrimid-6-yl)amino>ethoxy>methyl>-1,4-dihydropyridine (93117-91-0)

Guidance literature:

With triethylamine; In ethanol; for 4h; Heating;

DOI:10.1021/jm00123a009

Reference yield: 44.0%

4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-2-<<2-<(4-chloropyrimid-6-yl)amino>ethoxy>methyl>-1,4-dihydropyridine (93117-91-0) + methylamine (74-89-5) → 4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-2-<<2-<(4-(methylamino)pyrimidin-6-yl)amino>ethoxy>methyl>-1,4-dihydropyridine (93118-09-3)

Guidance literature:

In ethanol; for 17h; Heating;

DOI:10.1021/jm00123a009

upstream raw materials:

4,6-dichloropyrimidine

2-[(2-aminoethoxy)methyl]-4-(2,3-dichlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine

Downstream raw materials:

4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-2-<<2-<(4-(methylamino)pyrimidin-6-yl)amino>ethoxy>methyl>-1,4-dihydropyridine