methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(3-hydroxypropyl)-α-D-altroside

Base Information

• Chemical Name: methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(3-hydroxypropyl)-α-D-altroside
• CAS No.: 128142-89-2
• Molecular Formula: C₂₄H₃₀O₆
• Molecular Weight: 414.499
• Mol file: 128142-89-2.mol

Synonyms:methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(3-hydroxypropyl)-α-D-altroside

Chemical Property of methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(3-hydroxypropyl)-α-D-altroside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(3-hydroxypropyl)-α-D-altroside

There total 5 articles about methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(3-hydroxypropyl)-α-D-altroside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2,3-anhydro-4,6-benzylidene-α-D-allopyranoside (66537-92-6) → methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(3-hydroxypropyl)-α-D-altroside (128142-89-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / allylmagnesium chloride / tetrahydrofuran / 2 h

2: 1.) NaH, 2.) tetrabutylammonium iodide / 1.) THF, 15 min, 2.) 17 h

With allylmagnesium bromide; tetra-(n-butyl)ammonium iodide; sodium hydride; In tetrahydrofuran;

DOI:10.1071/CH9901681

Reference yield:

methyl 4,6-O-benzylidene-2-deoxy-2-(2-propenyl)-α-D-allohexopyranoside (126108-10-9) → methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(3-hydroxypropyl)-α-D-altroside (128142-89-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaH, 2.) tetrabutylammonium iodide / 1.) THF, 15 min, 2.) 17 h

With tetra-(n-butyl)ammonium iodide; sodium hydride;

DOI:10.1071/CH9901681

Reference yield:

benzyl bromide (100-39-0) → methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(3-hydroxypropyl)-α-D-altroside (128142-89-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaH, 2.) tetrabutylammonium iodide / 1.) THF, 15 min, 2.) 17 h

With tetra-(n-butyl)ammonium iodide; sodium hydride;

DOI:10.1071/CH9901681

upstream raw materials:

methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(prop-2-enyl)-α-D-altropyranoside

methyl 4,6-O-benzylidene-2-deoxy-2-(2-propenyl)-α-D-allohexopyranoside

benzyl bromide

methyl 2,3-anhydro-4,6-benzylidene-α-D-allopyranoside

Downstream raw materials:

methyl 3-O-benzyl-2-deoxy-2-C-(2-methoxycarbonylethyl)-6-O-phenylsulfonyl-α-D-altropyranoside

methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(2-methoxycarbonylpropyl)-α-D-altroside

methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-C-(2-methoxycarbonylethyl)-α-D-altroside

methyl 3-O-benzyl-6-O-t-butyldimethylsilyl-2-deoxy-2-C-(2-methoxycarbonylethyl)-α-D-arabino-hexosid-4-ulose