2-BIPHENYLMAGNESIUM BROMIDE

Base Information

• Chemical Name: 2-BIPHENYLMAGNESIUM BROMIDE
• CAS No.: 3315-91-1
• Molecular Formula: C12H9BrMg
• Molecular Weight: 257.412
• Hs Code.: 29319090
• European Community (EC) Number: 693-054-5
• Mol file: 3315-91-1.mol

Synonyms:Magnesium,4-biphenylylbromo- (7CI,8CI);1,1'-Biphenyl-4-ylmagnesium bromide;(p-Biphenylyl)magnesium bromide;(4-Biphenylyl)magnesium bromide;(4-Biphenylyl)bromomagnesium;4-Biphenylmagnesium bromide;[1,1'-Biphenyl]-4-ylbromomagnesium;Biphenyl-4-yl(bromo)magnesium;

Chemical Property of 2-BIPHENYLMAGNESIUM BROMIDE

Chemical Property:

• Boiling Point: 65 °C
• Flash Point: -40 °F
• PSA: 0.00000
• Density: 0.800 g/mL at 25 °C(lit.)
• LogP: 3.99940
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 255.97380
• Heavy Atom Count: 14
• Complexity: 218

Purity/Quality:

99% ^*data from raw suppliers

4-Biphenylmagnesium bromide solution 0.5 M in THF ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,C
• Hazard Codes: F+,C,F
• Statements: 12-19-22-34-67-14/15-11-37-14-40
• Safety Statements: 9-16-26-29-33-36/37/39-45-43

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=[C-]C=C2.[Mg+2].[Br-]

Technology Process of 2-BIPHENYLMAGNESIUM BROMIDE

There total 4 articles about 2-BIPHENYLMAGNESIUM BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-1,1'-biphenyl (92-66-0) → 4-biphenylylmagnesium bromide (3315-91-1)

Guidance literature:

Reference yield:

4-bromo-1,1'-biphenyl (92-66-0) + magnesium (7439-95-4) → 4-biphenylylmagnesium bromide (3315-91-1)

Guidance literature:

With iodine; In tetrahydrofuran; at 20 ℃;

DOI:10.1039/c5cc02277k

Reference yield:

phosgene (75-44-5) + 4-bromo-1,1'-biphenyl (92-66-0) + methyl magnesium (1+); bromide → 4-biphenylylmagnesium bromide (3315-91-1)

Guidance literature:

DOI:10.1021/jo01180a007

upstream raw materials:

phosgene

4-bromo-1,1'-biphenyl

magnesium

Downstream raw materials:

tris([1,1’-biphenyl]-4-yl)phosphine oxide

1,4-bis-(α-hydroxy-4,4'-diphenyl-benzhydryl)-benzene

5-(biphenyl-4-yl)-3,4-dihydro-2H-pyrrole

1,1-bis-biphenyl-4-yl-hexadecane

Refernces

• 1、 Zhao, Fei,Yu, Da-Gang,Zhu, Ru-Yi,Xi, Zhenfeng,Shi, Zhang-Jie. "Cross-coupling of aryl/alkenyl silyl ethers with grignard reagents through nickel-catalyzed CO bond activation". supporting information; experimental part. p. 1001 - 1003. Retrieved 2011/12/05.