benzyl prop-2-yn-1-yl carbonate

Base Information

• Chemical Name: benzyl prop-2-yn-1-yl carbonate
• CAS No.: 119649-68-2
• Molecular Formula: C₁₁H₁₀O₃
• Molecular Weight: 190.199
• Mol file: 119649-68-2.mol

Synonyms:benzyl prop-2-yn-1-yl carbonate

Chemical Property of benzyl prop-2-yn-1-yl carbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of benzyl prop-2-yn-1-yl carbonate

There total 2 articles about benzyl prop-2-yn-1-yl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

carbon dioxide (124-38-9,18923-20-1) + benzyl bromide (100-39-0) + propargyl alcohol (107-19-7) → benzyl prop-2-yn-1-yl carbonate (119649-68-2)

Guidance literature:

carbon dioxide; propargyl alcohol; With N,N-dimethyl acetamide; tetrabutylammomium bromide; potassium carbonate; at 20 ℃; for 1h; under 760.051 Torr;

benzyl bromide; With N,N-dimethyl acetamide; at 20 ℃; for 18h;

DOI:10.1039/c5cc04088d

Reference yield: 73.0%

propargyl alcohol (107-19-7) + benzyl chloroformate (501-53-1,94274-21-2) → benzyl prop-2-yn-1-yl carbonate (119649-68-2)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 16h;

DOI:10.1002/anie.201007992

Reference yield: 93.0%

benzyl prop-2-yn-1-yl carbonate (119649-68-2) + cyclohexanecarbaldehyde (2043-61-0) → Carbonic acid benzyl ester (S)-4-cyclohexyl-4-hydroxy-but-2-ynyl ester (790300-22-0)

Guidance literature:

benzyl prop-2-yn-1-yl carbonate; With (-)-N-methylephedrine; zinc trifluoromethanesulfonate; triethylamine; In toluene; at 20 ℃; for 0.5h;

cyclohexanecarbaldehyde; In toluene; at 20 ℃; for 4h;

DOI:10.1021/jo048985g

upstream raw materials:

propargyl alcohol

benzyl chloroformate

carbon dioxide

benzyl bromide

Downstream raw materials:

benzyl alcohol

Carbonic acid benzyl ester (S)-4-cyclohexyl-4-hydroxy-but-2-ynyl ester

Carbonic acid benzyl ester (Z)-(S)-4-cyclohexyl-4-hydroxy-but-2-enyl ester