1-Bromo-2,4,5-triisopropylbenzene

Base Information

• Chemical Name: 1-Bromo-2,4,5-triisopropylbenzene
• CAS No.: 131003-16-2
• Molecular Formula: C₁₅H₂₃Br
• Molecular Weight: 283.252
• Mol file: 131003-16-2.mol

Synonyms:bromo-2,4,6-triisopropylbenzene

Chemical Property of 1-Bromo-2,4,5-triisopropylbenzene

Chemical Property:

• Boiling Point: 307℃
• Flash Point: 132℃
• Density: 1.107

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Bromo-2,4,5-triisopropylbenzene

There total 8 articles about 1-Bromo-2,4,5-triisopropylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1,2,4-triisopropylbenzene (948-32-3) → bromo-2,4,6-triisopropylbenzene (131003-16-2)

Guidance literature:

With bromine; iron; In tetrachloromethane; 0 deg C, then ambient temperature, 90 min;

DOI:10.1055/s-1990-27028

Reference yield:

1,2,4-triisopropylbenzene (948-32-3) + iron (7439-89-6) → bromo-2,4,6-triisopropylbenzene (131003-16-2)

Guidance literature:

With bromine; In tetrachloromethane;

Reference yield:

1,2,4,5-tetraisopropylbenzene (635-11-0) → bromo-2,4,6-triisopropylbenzene (131003-16-2)

Guidance literature:

With tetrachloromethane; bromine; iron; at 0 ℃; Lichtausschluss;

DOI:10.1021/ja01252a062

upstream raw materials:

1,2,4-triisopropylbenzene

1,2,4,5-tetraisopropylbenzene

hydrogenchloride

2,4,5-tris-isopropylbenzene sulfonic acid

Downstream raw materials:

2,4,5-triisopropyl-benzoic acid amide

2,4,5-triisopropyl-benzonitrile

Refernces

• 1、 Jendralla, Heiner,Chen, Li-Jian. "Arylation of Phenols. Convenient, Regiospecific Methods for Mono- or Bis-p-fluorophenylations, Suitable for Large Scale Syntheses". . p. 827 - 833. Retrieved 2007/10/02.