(1R,7S,8S,9R)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.2.0^2,6]undecane-3,5-dione

Base Information

• Chemical Name: (1R,7S,8S,9R)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.2.0^2,6]undecane-3,5-dione
• CAS No.: 195197-69-4
• Molecular Formula: C₁₄H₁₅N₃O₄
• Molecular Weight: 289.291

Synonyms:(1R,7S,8S,9R)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.2.0^2,6]undecane-3,5-dione

Chemical Property of (1R,7S,8S,9R)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.2.0^2,6]undecane-3,5-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,7S,8S,9R)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.2.0^2,6]undecane-3,5-dione

There total 2 articles about (1R,7S,8S,9R)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.2.0^2,6]undecane-3,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-phenyl-2,4,6-triazatricyclo[5.2.2.02,6]undec-8-ene-3,5-dione (10316-53-7) → (1R,7S,8R,9S)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.2.02,6]undecane-3,5-dione (195197-67-2) + (1R,7S,8S,9R)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.2.02,6]undecane-3,5-dione (195197-69-4)

Guidance literature:

With osmium(VIII) oxide; 4-methylmorpholine N-oxide; In water; acetone; for 24h; Yield given. Yields of byproduct given; Ambient temperature;

DOI:10.1016/S0040-4039(97)01227-6

Reference yield:

4-Phenyl-1,2,4-triazolidine-3,5-dione (4233-33-4) → (1R,7S,8S,9R)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.2.02,6]undecane-3,5-dione (195197-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / CH₂Cl₂ / 0.5 h / Ambient temperature

2: N-methyl-morpholine oxide / OsO₄ / acetone; H₂O / 24 h / Ambient temperature

With 4-methylmorpholine N-oxide; osmium(VIII) oxide; In dichloromethane; water; acetone;

DOI:10.1016/S0040-4039(97)01227-6

Reference yield: 95.0%

2,2-dimethoxy-propane (77-76-9) + (1R,7S,8S,9R)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.2.02,6]undecane-3,5-dione (195197-69-4) → C17H19N3O4

Guidance literature:

With camphor-10-sulfonic acid; In dichloromethane; for 12h; Ambient temperature;

DOI:10.1016/S0040-4039(97)01227-6

upstream raw materials:

4-phenyl-2,4,6-triazatricyclo[5.2.2.0^2,6]undec-8-ene-3,5-dione

4-Phenyl-1,2,4-triazolidine-3,5-dione

Downstream raw materials:

N-((1R,2R,3S,4S)-4-Amino-2,3-dihydroxy-cyclohexyl)-2-phenyl-acetamide

N-((1S,2S,3R,4R)-2,3-Dihydroxy-4-phenylacetylamino-cyclohexyl)-2-phenyl-acetamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 195197-69-4 (1R,7S,8S,9R)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.2.0^2,6]undecane-3,5-dione

Send

Send

Metric Ton KG G Pound L ML

Send

Send