3,4-Dihydro-2H-1,4-benzoxazin-6-amine

Base Information

Chemical Name:3,4-Dihydro-2H-1,4-benzoxazin-6-amine
CAS No.:26011-57-4
Molecular Formula:C8H10N2O
Molecular Weight:150.18
Hs Code.:2934999090
DSSTox Substance ID:DTXSID80462905
Wikidata:Q82287536
Mol file:26011-57-4.mol

Synonyms:26011-57-4;3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-AMINE;3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZIN-6-AMINE;6-amino-3,4-dihydro-2h-1,4-benzoxazine;SCHEMBL127619;DTXSID80462905;UVUGDGRIYQQKIT-UHFFFAOYSA-N;BBA01157;AC5752;MFCD08272085;AKOS005136373;AB44324;AC-17558;SY130747;2H-1,4-Benzoxazin-6-amine,3,4-dihydro-;CS-0371069;3,4-dihydro-2H-benzo[1,4]oxazin-6-yl amine;EN300-6768029;A919356

Suppliers and Price of 3,4-Dihydro-2H-1,4-benzoxazin-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-AMINE 95.00%
5MG
$ 499.87

AK Scientific
3,4-Dihydro-2H-1,4-benzoxazin-6-amine
1g
$ 728.00

AccelPharmtech
3,4-dihydro-2H-benzo[b][1,4]oxazin-6-amine 97.00%
25G
$ 5120.00

AccelPharmtech
3,4-dihydro-2H-benzo[b][1,4]oxazin-6-amine 97.00%
5G
$ 2750.00

Total 13 raw suppliers

Chemical Property of 3,4-Dihydro-2H-1,4-benzoxazin-6-amine

Chemical Property:

Vapor Pressure:0.000117mmHg at 25°C
Refractive Index:1.6
Boiling Point:335.8 °C at 760 mmHg
PKA:5.87±0.20(Predicted)
Flash Point:156.9 °C
PSA：47.28000
Density:1.195 g/cm³
LogP:1.79230
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:150.079312947
Heavy Atom Count:11
Complexity:140

Purity/Quality:

97% ^*data from raw suppliers

3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(N1)C=C(C=C2)N

Technology Process of 3,4-Dihydro-2H-1,4-benzoxazin-6-amine

There total 8 articles about 3,4-Dihydro-2H-1,4-benzoxazin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 28226-22-4
6-nitro-1,4-benzoxazine

: 26011-57-4
3,4-Dihydro-2H-benzo[1,4]oxazin-6-ylamine

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; for 6h; Parr hydrogenator;

Reference yield: 65.0%

: 89976-75-0
6-amino-2H-1,4-benzoxazin-3(4H)-one

: 26011-57-4
3,4-Dihydro-2H-benzo[1,4]oxazin-6-ylamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at -20 - 70 ℃; for 3h;

Reference yield:

: 99-57-0
2-hydroxy-5-nitroaniline

: 26011-57-4
3,4-Dihydro-2H-benzo[1,4]oxazin-6-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 2.5 h / 125 °C

2: 230 mg / H₂ / Pd/C / ethanol / 2 h / 760 Torr

With hydrogen; potassium carbonate; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm049485i