2,4,6-Trichloropyridine-3-carboxylic acid

Base Information

Chemical Name:2,4,6-Trichloropyridine-3-carboxylic acid
CAS No.:69422-72-6
Molecular Formula:C₆H₂Cl₃NO₂
Molecular Weight:226.446
Hs Code.:2933399090
European Community (EC) Number:887-962-2
DSSTox Substance ID:DTXSID00596978
Wikidata:Q72510305
Mol file:69422-72-6.mol

Synonyms:69422-72-6;2,4,6-TRICHLOROPYRIDINE-3-CARBOXYLIC ACID;2,4,6-TRICHLORONICOTINIC ACID;MFCD09038102;3-Pyridinecarboxylic acid, 2,4,6-trichloro-;2,4,6-TRICHLORONICOTINICACID;SCHEMBL894222;DTXSID00596978;XORBTGOVTLGEOU-UHFFFAOYSA-N;AMY14139;AKOS015902719;AC-3179;SB21172;DS-16940;SY004335;3-Pyridinecarboxylicacid,2,4,6-trichloro-;DB-082208;CS-0135123;EN300-106605;A866839;Z1258943176

Suppliers and Price of 2,4,6-Trichloropyridine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4,6-Trichloropyridine-3-carboxylicAcid
100mg
$ 60.00

TRC
2,4,6-Trichloropyridine-3-carboxylicAcid
50mg
$ 45.00

Labseeker
2,4,6-Trichloropyridine-3-carboxylicAcid 95
10g
$ 770.00

Crysdot
2,4,6-Trichloronicotinicacid 97%
5g
$ 246.00

Chemenu
2,4,6-trichloronicotinicacid 97%
10g
$ 533.00

Chemenu
2,4,6-trichloronicotinicacid 97%
5g
$ 355.00

Chemenu
2,4,6-trichloronicotinicacid 97%
1g
$ 138.00

Ambeed
2,4,6-Trichloronicotinicacid 97%
1g
$ 94.00

Ambeed
2,4,6-Trichloronicotinicacid 97%
250mg
$ 34.00

Ambeed
2,4,6-Trichloronicotinicacid 97%
5g
$ 278.00

Total 32 raw suppliers

Chemical Property of 2,4,6-Trichloropyridine-3-carboxylic acid

Chemical Property:

Vapor Pressure:9.98E-06mmHg at 25°C
Refractive Index:1.618
Boiling Point:357.4 °C at 760 mmHg
PKA:0.49±0.28(Predicted)
Flash Point:169.9 °C
PSA：50.19000
Density:1.728 g/cm³
LogP:2.74000
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:224.915111
Heavy Atom Count:12
Complexity:190

Purity/Quality:

97% ^*data from raw suppliers

2,4,6-Trichloropyridine-3-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=C(N=C1Cl)Cl)C(=O)O)Cl

Technology Process of 2,4,6-Trichloropyridine-3-carboxylic acid

There total 4 articles about 2,4,6-Trichloropyridine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 16063-69-7
2,4,6-trichloropyridine

: 124-38-9,18923-20-1
carbon dioxide

: 69422-72-6
2,4,6-trichloronicotinoic acid

Guidance literature:: 2,4,6-trichloropyridine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

carbon dioxide; In tetrahydrofuran; hexane; at -78 - 0 ℃;
DOI:10.1021/jm0304966

Reference yield:

: 2587-00-0
2,6-dichloropyridine N-oxide

: 69422-72-6
2,4,6-trichloronicotinoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / 6 h / 100 °C

1.2: pH 8 - 9 / Cooling with ice

2.1: diisopropylamine; n-butyllithium / hexane; tetrahydrofuran / 1.5 h

2.2: 1 h / 20 °C

With n-butyllithium; diisopropylamine; trichlorophosphate; In tetrahydrofuran; hexane;

Reference yield:

: 2402-78-0
2,6-dichloropyridine

: 69422-72-6
2,4,6-trichloronicotinoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: trifluoroacetic acid; dihydrogen peroxide / 6 h / 100 °C

2.1: trichlorophosphate / 6 h / 100 °C

2.2: pH 8 - 9 / Cooling with ice

3.1: diisopropylamine; n-butyllithium / hexane; tetrahydrofuran / 1.5 h

3.2: 1 h / 20 °C

With n-butyllithium; dihydrogen peroxide; diisopropylamine; trifluoroacetic acid; trichlorophosphate; In tetrahydrofuran; hexane;