(2R,4R,5R)-4-fluoro-2-iodomethyl-5-<<(4-methylphenyl)sulfenyl>methyl>tetrahydrofuran

Base Information

Chemical Name:(2R,4R,5R)-4-fluoro-2-iodomethyl-5-<<(4-methylphenyl)sulfenyl>methyl>tetrahydrofuran
CAS No.:132113-36-1
Molecular Formula:C₁₃H₁₆FIOS
Molecular Weight:366.238
Hs Code.:

Synonyms:(2R,4R,5R)-4-fluoro-2-iodomethyl-5-<<(4-methylphenyl)sulfenyl>methyl>tetrahydrofuran

Suppliers and Price of (2R,4R,5R)-4-fluoro-2-iodomethyl-5-<<(4-methylphenyl)sulfenyl>methyl>tetrahydrofuran

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,4R,5R)-4-fluoro-2-iodomethyl-5-<<(4-methylphenyl)sulfenyl>methyl>tetrahydrofuran

Chemical Property:

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Technology Process of (2R,4R,5R)-4-fluoro-2-iodomethyl-5-<<(4-methylphenyl)sulfenyl>methyl>tetrahydrofuran

There total 1 articles about (2R,4R,5R)-4-fluoro-2-iodomethyl-5-<<(4-methylphenyl)sulfenyl>methyl>tetrahydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 127227-66-1
(4R,5R)-4-fluoro-5-hydroxy-6-<(4-methylphenyl)sulfenyl>hex-1-ene

: 132113-39-4
(2S,4R,5R)-4-fluoro-2-iodomethyl-5-<<(4-methylphenyl)sulfenyl>methyl>tetrahydrofuran

: 132113-36-1
(2R,4R,5R)-4-fluoro-2-iodomethyl-5-<<(4-methylphenyl)sulfenyl>methyl>tetrahydrofuran

Guidance literature:: With iodine; sodium hydrogencarbonate; In acetonitrile; for 72h; Yield given. Yields of byproduct given; Ambient temperature;

Reference yield: 70.0%

: 132113-36-1
(2R,4R,5R)-4-fluoro-2-iodomethyl-5-<<(4-methylphenyl)sulfenyl>methyl>tetrahydrofuran

: 124-40-3
dimethyl amine

: 142722-63-2
(2R,4R,5R)-2-<(dimethylamino)methyl>-4-fluoro-5-<<(4-methylphenyl)sylfenyl>methyl>tetrahydrofuran

Guidance literature:: In ethanol; at 90 ℃; for 3h;
DOI:10.1021/jm00095a003

Reference yield:

: 132113-36-1
(2R,4R,5R)-4-fluoro-2-iodomethyl-5-<<(4-methylphenyl)sulfenyl>methyl>tetrahydrofuran

: 132113-41-8,142722-62-1
(2R,4R,5S)-2-<(dimethylamino)methyl>-4-fluoro-5-methyltetrahydrofuran

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / ethanol / 3 h / 90 °C

2: H₂ / Raney Ni / ethanol / 0.08 h / Heating

With hydrogen; nickel; In ethanol;
DOI:10.1021/jm00095a003