N-((1R,2S)-2-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carbonyl)-4-(methylamino)cyclohexyl)benzamide trifluoroacetate

Base Information

Chemical Name:N-((1R,2S)-2-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carbonyl)-4-(methylamino)cyclohexyl)benzamide trifluoroacetate
CAS No.:1105702-31-5
Molecular Formula:C₂HF₃O₂*C₂₈H₃₆ClN₃O₃
Molecular Weight:612.089
Hs Code.:

Synonyms:N-((1R,2S)-2-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carbonyl)-4-(methylamino)cyclohexyl)benzamide trifluoroacetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-((1R,2S)-2-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carbonyl)-4-(methylamino)cyclohexyl)benzamide trifluoroacetate

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Technology Process of N-((1R,2S)-2-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carbonyl)-4-(methylamino)cyclohexyl)benzamide trifluoroacetate

There total 1 articles about N-((1R,2S)-2-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carbonyl)-4-(methylamino)cyclohexyl)benzamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

: 1105702-29-1
N-((1R,2S)-2-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carbonyl)-4-oxocyclohexyl)benzamide

: 74-89-5
methylamine

: 1105702-31-5
N-((1R,2S)-2-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carbonyl)-4-(methylamino)cyclohexyl)benzamide trifluoroacetate

Guidance literature:: N-((1R,2S)-2-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carbonyl)-4-oxocyclohexyl)benzamide; methylamine; In tetrahydrofuran; dichloromethane; at 25 ℃; for 19h; Molecular sieve;

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; dichloromethane; for 20h;