1-[2-(2-Bromophenyl)acetyl]-1H-indole-3-carboxaldehyde

Base Information

Chemical Name:1-[2-(2-Bromophenyl)acetyl]-1H-indole-3-carboxaldehyde
CAS No.:171734-95-5
Molecular Formula:C₁₇H₁₂BrNO₂
Molecular Weight:342.192
Hs Code.:
DSSTox Substance ID:DTXSID901209509

Synonyms:1-[2-(2-Bromophenyl)acetyl]-1H-indole-3-carboxaldehyde;DTXSID901209509;171734-95-5

Suppliers and Price of 1-[2-(2-Bromophenyl)acetyl]-1H-indole-3-carboxaldehyde

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-[2-(2-Bromophenyl)acetyl]-1H-indole-3-carboxaldehyde

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:341.00514
Heavy Atom Count:21
Complexity:400

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CC(=O)N2C=C(C3=CC=CC=C32)C=O)Br

Technology Process of 1-[2-(2-Bromophenyl)acetyl]-1H-indole-3-carboxaldehyde

There total 1 articles about 1-[2-(2-Bromophenyl)acetyl]-1H-indole-3-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

: 18698-97-0
ortho-bromophenylacetic acid

: 171734-95-5
1-<2-(2-bromophenyl)-1-oxoethyl>-1H-indole-3-carboxaldehyde

Guidance literature:: With dichloro bis(acetonitrile) palladium(II); N-benzyl-N,N,N-triethylammonium chloride; ammonium formate;

Reference yield: 85.0%

: 171734-95-5
1-<2-(2-bromophenyl)-1-oxoethyl>-1H-indole-3-carboxaldehyde

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

Guidance literature:: With dichloro bis(acetonitrile) palladium(II); N-benzyl-N,N,N-triethylammonium chloride; In N,N-dimethyl-formamide;

Reference yield:

: 171734-95-5
1-<2-(2-bromophenyl)-1-oxoethyl>-1H-indole-3-carboxaldehyde

: 116611-37-1
2-(1H-indol-1-yl)-1-phenylethan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / Pd(CH₃CN)2Cl₂, Bn(C₂H₅)3NCl / dimethylformamide

2: 87 percent / K₂CO₃ / acetonitrile / Heating

3: 65 percent / Pd(OAc)2 / acetic acid / 4 h / Heating

With palladium diacetate; dichloro bis(acetonitrile) palladium(II); N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; In acetic acid; N,N-dimethyl-formamide; acetonitrile;