1-({[4-({2-[(ethyloxy)carbonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}oxy)phenyl]amino}carbonyl)cyclopropanecarboxylic acid

Base Information

• Chemical Name: 1-({[4-({2-[(ethyloxy)carbonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}oxy)phenyl]amino}carbonyl)cyclopropanecarboxylic acid
• CAS No.: 1021950-22-0
• Molecular Formula: C₂₁H₁₉N₃O₆
• Molecular Weight: 409.398
• Mol file: 1021950-22-0.mol

Synonyms:1-({[4-({2-[(ethyloxy)carbonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}oxy)phenyl]amino}carbonyl)cyclopropanecarboxylic acid

Chemical Property of 1-({[4-({2-[(ethyloxy)carbonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}oxy)phenyl]amino}carbonyl)cyclopropanecarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-({[4-({2-[(ethyloxy)carbonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}oxy)phenyl]amino}carbonyl)cyclopropanecarboxylic acid

There total 1 articles about 1-({[4-({2-[(ethyloxy)carbonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}oxy)phenyl]amino}carbonyl)cyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(chlorocarbonyl)cyclopropane-1-carboxylic acid (40258-99-9) + ethyl 4-[(4-aminophenyl)oxy]-1H-pyrrolo[2,3-b]pyridine-2-carboxylate (1021950-18-4) → 1-({[4-({2-[(ethyloxy)carbonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}oxy)phenyl]amino}carbonyl)cyclopropanecarboxylic acid (1021950-22-0)

Guidance literature:

In tetrahydrofuran;

Reference yield:

1-({[4-({2-[(ethyloxy)carbonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}oxy)phenyl]amino}carbonyl)cyclopropanecarboxylic acid (1021950-22-0) + 4-fluoroaniline (371-40-4) → C27H23FN4O5 (1021950-55-9)

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 5h;

upstream raw materials:

1-(chlorocarbonyl)cyclopropane-1-carboxylic acid

ethyl 4-[(4-aminophenyl)oxy]-1H-pyrrolo[2,3-b]pyridine-2-carboxylate

Downstream raw materials:

C₂₇H₂₃FN₄O₅