[6-(2-benzofuranyl)-1-bromo-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester

Base Information

Chemical Name:[6-(2-benzofuranyl)-1-bromo-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester
CAS No.:262426-73-3
Molecular Formula:C₂₇H₂₄BrNO₄
Molecular Weight:506.396
Hs Code.:

Synonyms:[6-(2-benzofuranyl)-1-bromo-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester

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Chemical Property of [6-(2-benzofuranyl)-1-bromo-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester

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Technology Process of [6-(2-benzofuranyl)-1-bromo-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester

There total 1 articles about [6-(2-benzofuranyl)-1-bromo-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 174347-73-0
[6-(2-benzofuranyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester

: 262426-73-3
[6-(2-benzofuranyl)-1-bromo-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester

Guidance literature:: With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; for 2h; Heating / reflux;

Reference yield: 86.3%

: 67-56-1
methanol

: 262426-73-3
[6-(2-benzofuranyl)-1-bromo-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester

: 262426-74-4
[6-(2-benzofuranyl)-2,3-dihydro-2,2-dimethyl-1-methoxy-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid methyl ester

: [6-(2-benzofuranyl)-2,3-dihydro-2,2-dimethyl-1-methoxy-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester

Guidance literature:: at 20 ℃; for 0.5 - 0.75h;

Reference yield: 77.0%

: 262426-73-3
[6-(2-benzofuranyl)-1-bromo-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester

: 262426-66-4
[6-(2-benzofuranyl)-2,3-dihydro-2,2-dimethyl-1-methoxy-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid

Guidance literature:: [6-(2-benzofuranyl)-1-bromo-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]oxoacetic acid ethyl ester; With sodium hydroxide; In methanol; for 2h; Heating / reflux;

With hydrogenchloride; In water;