2-Amino-5-chloro-4-nitrobenzoic acid

Base Information

Chemical Name:2-Amino-5-chloro-4-nitrobenzoic acid
CAS No.:34649-02-0
Molecular Formula:C7H5ClN2O4
Molecular Weight:216.581
Hs Code.:2922499990
Mol file:34649-02-0.mol

Synonyms:2-Amino-4-nitro-5-chlorobenzoicacid;2-Amino-5-chloro-4-nitrobenzoic acid;5-Chloro-4-nitroanthranilic acid;

Suppliers and Price of 2-Amino-5-chloro-4-nitrobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-5-chloro-4-nitrobenzoicAcid
500mg
$ 950.00

Crysdot
2-Amino-5-chloro-4-nitrobenzoicacid 95+%
1g
$ 339.00

Chemcia Scientific
2-Amino-5-chloro-4-nitro-benzoicacid 95%
2.5 G
$ 1185.00

American Custom Chemicals Corporation
2-AMINO-5-CHLORO-4-NITROBENZOIC ACID 98.00%
10G
$ 1940.40

Alichem
2-Amino-5-chloro-4-nitrobenzoicacid
1g
$ 400.00

Total 15 raw suppliers

Chemical Property of 2-Amino-5-chloro-4-nitrobenzoic acid

Chemical Property:

Melting Point:268-270℃ (DEC.)
PSA：109.14000
Density:1.691
LogP:2.63300
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-5-chloro-4-nitrobenzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-Amino-5-chloro-4-nitrobenzoic Acid (cas# 34649-02-0) is a useful reagent in the preparation of N-?guanidino substituted 2,?4-?diamino-?5-?carbonylguanidine molecules related to amiloride that inhibits the sodium-?calcium exchanger in rat insulinoma cells (RINm5F) and human platelets.

Technology Process of 2-Amino-5-chloro-4-nitrobenzoic acid

There total 7 articles about 2-Amino-5-chloro-4-nitrobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 530084-00-5
methyl 2-amino-5-chloro-4-nitrobenzoate

: 34649-02-0
2-amino-5-chloro-4-nitrobenzoic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 2h; Heating;
DOI:10.1016/S0014-827X(02)01281-8

Reference yield: 92.2%

: 34649-01-9
2-acetylamino-5-chloro-4-nitrobenzoic acid

: 34649-02-0
2-amino-5-chloro-4-nitrobenzoic acid

Guidance literature:: With hydrogenchloride; In water; for 3h; Reflux;

Reference yield:

: 3558-19-8
methyl 2-amino-4-nitrobenzoate

: 34649-02-0
2-amino-5-chloro-4-nitrobenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 37 percent / SO₂Cl₂; glac. AcOH / 30 °C

2: 100 percent / aq. NaOH / ethanol / 2 h / Heating

With sodium hydroxide; sulfuryl dichloride; acetic acid; In ethanol;
DOI:10.1016/S0014-827X(02)01281-8