2-Amino-4-(benzyloxy)-5-methoxybenzonitrile

Base Information

Chemical Name:2-Amino-4-(benzyloxy)-5-methoxybenzonitrile
CAS No.:385785-02-4
Molecular Formula:C15H14 N2 O2
Molecular Weight:254.288
Hs Code.:2926909090
DSSTox Substance ID:DTXSID90470839
Nikkaji Number:J3.633.332D
Wikidata:Q82299017
Mol file:385785-02-4.mol

Synonyms:2-AMINO-4-(BENZYLOXY)-5-METHOXYBENZONITRILE;385785-02-4;2-amino-5-methoxy-4-phenylmethoxybenzonitrile;Benzonitrile, 2-amino-5-methoxy-4-(phenylmethoxy)-;2-amino-4-benzyloxy-5-methoxybenzonitrile;SCHEMBL3488326;DTXSID90470839;GAOSRWTZALOJOO-UHFFFAOYSA-N;AR2297;MFCD08234438;AKOS015965542;SB81553;2-amino-4benzyloxy-5-methoxybenzonitrile;AS-45318;2-amino-4-benzyloxy-5-methoxy benzonitrile;BB 0256631;CS-0022486;A912917

Suppliers and Price of 2-Amino-4-(benzyloxy)-5-methoxybenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Amino-4-(benzyloxy)-5-methoxybenzonitrile 97%
1g
$ 545.00

Biosynth Carbosynth
2-Amino-4-(Benzyloxy)-5-Methoxybenzonitrile
250 mg
$ 275.00

Biosynth Carbosynth
2-Amino-4-(Benzyloxy)-5-Methoxybenzonitrile
100 mg
$ 219.00

Biosynth Carbosynth
2-Amino-4-(Benzyloxy)-5-Methoxybenzonitrile
50 mg
$ 137.00

Biosynth Carbosynth
2-Amino-4-(Benzyloxy)-5-Methoxybenzonitrile
25 mg
$ 70.00

Biosynth Carbosynth
2-Amino-4-(Benzyloxy)-5-Methoxybenzonitrile
500 mg
$ 440.00

American Custom Chemicals Corporation
2-AMINO-4-(BENZYLOXY)-5-METHOXYBENZONITRILE 95.00%
1G
$ 1552.32

American Custom Chemicals Corporation
2-AMINO-4-(BENZYLOXY)-5-METHOXYBENZONITRILE 95.00%
100MG
$ 782.23

American Custom Chemicals Corporation
2-AMINO-4-(BENZYLOXY)-5-METHOXYBENZONITRILE 95.00%
5G
$ 4669.09

AK Scientific
2-Amino-4-(benzyloxy)-5-methoxybenzonitrile
5g
$ 1780.00

Total 11 raw suppliers

Chemical Property of 2-Amino-4-(benzyloxy)-5-methoxybenzonitrile

Chemical Property:

PSA：68.27000
LogP:3.30928
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:254.105527694
Heavy Atom Count:19
Complexity:319

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-4-(benzyloxy)-5-methoxybenzonitrile 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C(=C1)C#N)N)OCC2=CC=CC=C2

Technology Process of 2-Amino-4-(benzyloxy)-5-methoxybenzonitrile

There total 7 articles about 2-Amino-4-(benzyloxy)-5-methoxybenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 385784-84-9
4-(benzyloxy)-5-methoxy-2-nitrobenzonitrile

: 385785-02-4
2-amino-4-(benzyloxy)-5-methoxybenzonitrile

Guidance literature:: With sodium dithionite; Na₂S₂O₄; tetrabutyl-ammonium chloride; sodium hydrogencarbonate; In methanol; dichloromethane; water;

Reference yield:

: 52805-34-2
4-(benzyloxy)-3-methoxybenzonitrile

: 385785-02-4
2-amino-4-(benzyloxy)-5-methoxybenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / HNO₃; AcOH / 20 h / 20 °C

2: 84 percent / aq. Na₂S₂O₄; Bu₄NCl / CH₂Cl₂ / 20 h / 20 °C

With sodium dithionite; tetrabutyl-ammonium chloride; nitric acid; acetic acid; In dichloromethane;
DOI:10.1021/jm050786h

Reference yield:

: 100-39-0
benzyl bromide

: 385785-02-4
2-amino-4-(benzyloxy)-5-methoxybenzonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 20 °C

2: nitric acid; acetic anhydride / 0 - 20 °C

3: water; iron; ammonium chloride / isopropyl alcohol / Reflux

With water; nitric acid; acetic anhydride; iron; potassium carbonate; ammonium chloride; In N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/jm200903z