N-cyano-N'-[2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethyl]-N''-[4-[N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methylamino]butyl]guanidine

Base Information

Chemical Name:N-cyano-N'-[2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethyl]-N''-[4-[N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methylamino]butyl]guanidine
CAS No.:149841-77-0
Molecular Formula:C₂₉H₄₁N₁₁OS₂
Molecular Weight:623.85
Hs Code.:

Synonyms:N-cyano-N'-[2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethyl]-N''-[4-[N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methylamino]butyl]guanidine

Suppliers and Price of N-cyano-N'-[2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethyl]-N''-[4-[N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methylamino]butyl]guanidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-cyano-N'-[2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethyl]-N''-[4-[N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methylamino]butyl]guanidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-cyano-N'-[2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethyl]-N''-[4-[N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methylamino]butyl]guanidine

There total 8 articles about N-cyano-N'-[2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethyl]-N''-[4-[N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methylamino]butyl]guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: N¹-{2-[(4-Methoxy-benzyl)-pyridin-2-yl-amino]-ethyl}-N¹-methyl-butane-1,4-diamine

: 101309-33-5
C₁₅H₁₇N₇OS₂

: 149841-77-0
N-cyano-N'-[2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethyl]-N''-[4-[N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methylamino]butyl]guanidine

Guidance literature:: In acetonitrile; for 16h; Reflux;
DOI:10.3390/molecules181114186

Reference yield:

: 109-04-6
2-bromo-pyridine

: 149841-77-0
N-cyano-N'-[2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethyl]-N''-[4-[N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methylamino]butyl]guanidine

Guidance literature:: Multi-step reaction with 6 steps

1.1: pyridine / 3 h / Reflux

2.1: sodium hydride / dimethyl sulfoxide / 20 - 85 °C / Inert atmosphere

2.2: 12 h / 20 - 85 °C / Inert atmosphere

3.1: sodium hydroxide / diethyl ether / Cooling with ice

4.1: potassium iodide; sodium carbonate / acetonitrile; N,N-dimethyl-formamide / 2 h / 60 °C

5.1: lithium aluminium tetrahydride / diethyl ether / 2 h / 20 °C

6.1: acetonitrile / 16 h / Reflux

With pyridine; lithium aluminium tetrahydride; sodium hydride; sodium carbonate; potassium iodide; sodium hydroxide; In diethyl ether; dimethyl sulfoxide; N,N-dimethyl-formamide; acetonitrile;
DOI:10.3390/molecules181114186

Reference yield:

: 109912-28-9
N-(4-methoxybenzyl)-N-2-pyridinyl-1,2-ethanediamine

: 149841-77-0
N-cyano-N'-[2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethyl]-N''-[4-[N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methylamino]butyl]guanidine

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / diethyl ether / Cooling with ice

2: potassium iodide; sodium carbonate / acetonitrile; N,N-dimethyl-formamide / 2 h / 60 °C

3: lithium aluminium tetrahydride / diethyl ether / 2 h / 20 °C

4: acetonitrile / 16 h / Reflux

With lithium aluminium tetrahydride; sodium carbonate; potassium iodide; sodium hydroxide; In diethyl ether; N,N-dimethyl-formamide; acetonitrile;
DOI:10.3390/molecules181114186