2-[4-[[carboxymethyl-(5-methyl-2-p-tolyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester

Base Information

Chemical Name:2-[4-[[carboxymethyl-(5-methyl-2-p-tolyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester
CAS No.:866641-18-1
Molecular Formula:C₂₉H₃₆N₂O₆
Molecular Weight:508.615
Hs Code.:

Synonyms:2-[4-[[carboxymethyl-(5-methyl-2-p-tolyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester

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Chemical Property of 2-[4-[[carboxymethyl-(5-methyl-2-p-tolyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester

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Technology Process of 2-[4-[[carboxymethyl-(5-methyl-2-p-tolyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester

There total 3 articles about 2-[4-[[carboxymethyl-(5-methyl-2-p-tolyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 866641-17-0
ethyl 2-(4-{[(2-tert-butoxy-2-oxoethyl){[5-methyl-2-(4-methyl phenyl)-1,3-oxazol-4-yl]methyl}amino]methyl}-2,6-dimethylphenoxy)-2-methylpropanoate

: 866641-18-1
2-[4-[[carboxymethyl-(5-methyl-2-p-tolyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 48h;

Reference yield:

: 866640-84-8
ethyl 2-(4-{[(2-tert-butoxy-2-oxoethyl)amino]methyl}-2,6-dimethylphenoxy)-2-methylpropanoate

: 866641-18-1
2-[4-[[carboxymethyl-(5-methyl-2-p-tolyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 2 h / Reflux

2: trifluoroacetic acid / dichloromethane / 120 h / 0 - 20 °C

With potassium carbonate; trifluoroacetic acid; In dichloromethane; acetonitrile;
DOI:10.1248/cpb.c15-00221

Reference yield:

: 137090-44-9
[5-Methyl-2-(4-methylphenyl)-4-oxazolyl]methyl Chloride

: 866641-18-1
2-[4-[[carboxymethyl-(5-methyl-2-p-tolyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 2 h / Reflux

2: trifluoroacetic acid / dichloromethane / 120 h / 0 - 20 °C

With potassium carbonate; trifluoroacetic acid; In dichloromethane; acetonitrile;
DOI:10.1248/cpb.c15-00221