2-[[2-[[2-[[2-[[2-[[5-Amino-2-[[5-amino-2-[[1-[6-amino-2-[[1-[2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoic acid

Base Information

• Chemical Name: 2-[[2-[[2-[[2-[[2-[[5-Amino-2-[[5-amino-2-[[1-[6-amino-2-[[1-[2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoic acid
• CAS No.: 71977-09-8
• Molecular Formula: C63H97N17O14S
• Molecular Weight: 1348.63
• DSSTox Substance ID: DTXSID60407793
• Mol file: 71977-09-8.mol

Synonyms:71977-09-8;Substance P free acid;[Met-OH11]-Substance P;2-[[2-[[2-[[2-[[2-[[5-amino-2-[[5-amino-2-[[1-[6-amino-2-[[1-[2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoic acid;Substance P, 11-L-methionine-;DTXSID60407793;[Met-OH11]-Substance P, >=97% (HPLC)

Chemical Property of 2-[[2-[[2-[[2-[[2-[[5-Amino-2-[[5-amino-2-[[1-[6-amino-2-[[1-[2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoic acid

Chemical Property:

• PSA: 536.14000
• Density: 1.41 g/cm³
• LogP: 4.09310
• Storage Temp.: −20°C
• XLogP3: -3.9
• Hydrogen Bond Donor Count: 15
• Hydrogen Bond Acceptor Count: 18
• Rotatable Bond Count: 42
• Exact Mass: 1347.71216201
• Heavy Atom Count: 95
• Complexity: 2620

Purity/Quality:

99%, ^*data from raw suppliers

[Met-OH11]-Substance P ≥97% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CC(C(=O)NC(CCSC)C(=O)O)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N
• Uses: A neurokinin NK-1 receptor agonist

Technology Process of 2-[[2-[[2-[[2-[[2-[[5-Amino-2-[[5-amino-2-[[1-[6-amino-2-[[1-[2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoic acid

There total 1 articles about 2-[[2-[[2-[[2-[[2-[[5-Amino-2-[[5-amino-2-[[1-[6-amino-2-[[1-[2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

BOC-glycine (4530-20-5) + N-tert-butoxycarbonyl-L-leucine (13139-15-6,53296-34-7) + N-tert-butoxycarbonyl-L-methionine (2488-15-5) + N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) → substance P (71977-09-8)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1021/jm00343a012

Reference yield:

substance P (71977-09-8) + 3-amino-4-hydroxytoluene (95-84-1) → C70H101N17O16S

Guidance literature:

With potassium hexacyanoferrate(III); In aq. phosphate buffer; acetonitrile; at 20 ℃; for 0.5h; pH=7.5;

DOI:10.1021/ja500728c

Reference yield:

isatropolone A (2097813-40-4) + substance P (71977-09-8) → C87H120N17O22S(1+)

Guidance literature:

With triethylamine; In water; at 37 ℃; for 2h;

DOI:10.1002/anie.201701223

upstream raw materials:

BOC-glycine

N-tert-butoxycarbonyl-L-leucine

N-tert-butoxycarbonyl-L-methionine

N-tert-butoxycarbonyl-L-phenylalanine

Downstream raw materials:

C₇₄H₁₀₃N₁₇O₁₈S

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 71977-09-8 SUBSTANCE P

Send

Send

Metric Ton KG G Pound L ML

Send

Send