(R)-(+)-4-Chloromethyl-2,2-Dimethyl-1,3-Dioxolane

Base Information Edit

Chemical Name:(R)-(+)-4-Chloromethyl-2,2-Dimethyl-1,3-Dioxolane
CAS No.:57044-24-3
Molecular Formula:C6H11ClO2
Molecular Weight:150.605
Hs Code.:29329990
European Community (EC) Number:629-411-9
UNII:CTC27N3WX9
Nikkaji Number:J451.160C
Mol file:57044-24-3.mol

Synonyms:57044-24-3;(R)-(+)-4-Chloromethyl-2,2-Dimethyl-1,3-Dioxolane;(R)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane;(4R)-4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane;(R)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane;(R)-(+)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane;1,3-Dioxolane, 4-(chloromethyl)-2,2-dimethyl-, (4R)-;CTC27N3WX9;(R)-3-chloro-1,2-propanediol acetonide;4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane, (+)-;(R )-4-CHLOROMETHYL-2,2 -DIMETHYL-1,3-DIOXOLANE;MFCD00273371;UNII-CTC27N3WX9;SCHEMBL1204186;(R)-(+)-4-Chloromethyl-2,2-dimethyl--1,3-dioxolane;BNPOTXLWPZOESZ-YFKPBYRVSA-N;AMY14972;AKOS006239595;AKOS015848752;AC-6919;CS-W002598;AC-18287;AS-33337;A8435;C2265;EN300-7151020;(R)-2,2-Dimethyl-4-Chloromethyl-1,3-Dioxolane;J-513687;(R)-(+)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane, 98%

Suppliers and Price of (R)-(+)-4-Chloromethyl-2,2-Dimethyl-1,3-Dioxolane

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane
25g
$ 790.00

TCI Chemical
(R)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane >98.0%(GC)
5g
$ 71.00

TCI Chemical
(R)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane >98.0%(GC)
25g
$ 212.00

SynQuest Laboratories
(R)-(+)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane
25 g
$ 359.00

Sigma-Aldrich
(R)-(+)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane 98%
5g
$ 123.00

Medical Isotopes, Inc.
(R)-(+)-3-Chloro-1,2-propanediolacetonide
25 g
$ 1390.00

Chem-Impex
(R)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane,98%(GC) 98%(GC)
25G
$ 360.64

Chem-Impex
(R)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane,≥98%(GC)Hazmat ≥98%(GC)
5G
$ 103.67

Biosynth Carbosynth
(R)-3-Chloro-1,2-propandiol acetonide
5 g
$ 93.00

Biosynth Carbosynth
(R)-3-Chloro-1,2-propandiol acetonide
10 g
$ 161.00

Total 42 raw suppliers

Chemical Property of (R)-(+)-4-Chloromethyl-2,2-Dimethyl-1,3-Dioxolane Edit

Chemical Property:

Refractive Index:n20/D 1.434(lit.)
Boiling Point:156 °C at 760 mmHg
Flash Point:54.5 °C
PSA：18.46000
Density:1.103 g/cm³
LogP:1.37670
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:150.0447573
Heavy Atom Count:9
Complexity:103

Purity/Quality:

97% ^*data from raw suppliers

(R)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 10-41
Safety Statements: 16-26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(OCC(O1)CCl)C
Isomeric SMILES:CC1(OC[C@@H](O1)CCl)C
Uses (R)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is often used in biosynthetic preparations. Utilized in the preparation of both enantiomers of the orally active antifungal azolic agent ketoconazole.

Technology Process of (R)-(+)-4-Chloromethyl-2,2-Dimethyl-1,3-Dioxolane

There total 5 articles about (R)-(+)-4-Chloromethyl-2,2-Dimethyl-1,3-Dioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%