(benzoxy) 3-[1,2-di-(10-undecenyl)-sn-glyceroxy] (N,N-diisopropylamino)phosphine

Base Information

• Chemical Name: (benzoxy) 3-[1,2-di-(10-undecenyl)-sn-glyceroxy] (N,N-diisopropylamino)phosphine
• CAS No.: 188950-57-4
• Molecular Formula: C₃₈H₆₈NO₄P
• Molecular Weight: 633.936
• Mol file: 188950-57-4.mol

Synonyms:(benzoxy) 3-[1,2-di-(10-undecenyl)-sn-glyceroxy] (N,N-diisopropylamino)phosphine

Chemical Property of (benzoxy) 3-[1,2-di-(10-undecenyl)-sn-glyceroxy] (N,N-diisopropylamino)phosphine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (benzoxy) 3-[1,2-di-(10-undecenyl)-sn-glyceroxy] (N,N-diisopropylamino)phosphine

There total 3 articles about (benzoxy) 3-[1,2-di-(10-undecenyl)-sn-glyceroxy] (N,N-diisopropylamino)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(benzyloxy)chloro(diisopropylamino)phosphane (128753-68-4) + 1,2-di-(10-undecenyl)-sn-glycerol (188950-56-3) → (benzoxy) 3-[1,2-di-(10-undecenyl)-sn-glyceroxy] (N,N-diisopropylamino)phosphine (188950-57-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 1.41667h;

DOI:10.1002/(SICI)1099-1344(199703)39:3<251::AID-JLCR964>3.0.CO;2-Y

Reference yield:

1-undecen-11-ylbromide (7766-50-9) → (benzoxy) 3-[1,2-di-(10-undecenyl)-sn-glyceroxy] (N,N-diisopropylamino)phosphine (188950-57-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 82 percent / NaH / dimethylformamide / 2 h / Ambient temperature

2: 98 percent / DDQ / CH₂Cl₂ / 3 h / Ambient temperature

3: 95 percent / i-Pr₂NEt / CH₂Cl₂ / 1.42 h / 0 - 20 °C

With sodium hydride; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/(SICI)1099-1344(199703)39:3<251::AID-JLCR964>3.0.CO;2-Y

Reference yield:

1,2-di-(10-undecenyl)-3-(p-methoxybenzyl)-sn-glycerol (188950-55-2) → (benzoxy) 3-[1,2-di-(10-undecenyl)-sn-glyceroxy] (N,N-diisopropylamino)phosphine (188950-57-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / DDQ / CH₂Cl₂ / 3 h / Ambient temperature

2: 95 percent / i-Pr₂NEt / CH₂Cl₂ / 1.42 h / 0 - 20 °C

With N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane;

DOI:10.1002/(SICI)1099-1344(199703)39:3<251::AID-JLCR964>3.0.CO;2-Y

upstream raw materials:

(benzyloxy)chloro(diisopropylamino)phosphane

1,2-di-(10-undecenyl)-sn-glycerol

1-undecen-11-ylbromide

1,2-di-(10-undecenyl)-3-(p-methoxybenzyl)-sn-glycerol

Downstream raw materials:

benzyl 3-[1,2-di-(10-undecenyl)-sn-glyceryl] 1-[2,6-di-O-benzoxymethyl-3-O-benzyl-4,5-O-(p-methoxybenzyl)-D-myo-inosityl] phosphate

benzyl 3-[1,2-di-(10-undecenyl)-sn-glyceryl] 1-O-(2,6-di-O-benzoxymethyl-3-O-benzyl-D-myo-inosityl) phosphate