6-bromo-N-<6-methoxy-4-methyl-5-<3-(trifluoromethyl)phenoxy>-8-quinolinyl>hexanamide

Base Information

Chemical Name:6-bromo-N-<6-methoxy-4-methyl-5-<3-(trifluoromethyl)phenoxy>-8-quinolinyl>hexanamide
CAS No.:83547-30-2
Molecular Formula:C₂₄H₂₄BrF₃N₂O₃
Molecular Weight:525.365
Hs Code.:

Synonyms:6-bromo-N-<6-methoxy-4-methyl-5-<3-(trifluoromethyl)phenoxy>-8-quinolinyl>hexanamide

Suppliers and Price of 6-bromo-N-<6-methoxy-4-methyl-5-<3-(trifluoromethyl)phenoxy>-8-quinolinyl>hexanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-bromo-N-<6-methoxy-4-methyl-5-<3-(trifluoromethyl)phenoxy>-8-quinolinyl>hexanamide

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Technology Process of 6-bromo-N-<6-methoxy-4-methyl-5-<3-(trifluoromethyl)phenoxy>-8-quinolinyl>hexanamide

There total 1 articles about 6-bromo-N-<6-methoxy-4-methyl-5-<3-(trifluoromethyl)phenoxy>-8-quinolinyl>hexanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 22809-37-6
6-bromohexanoyl chloride

: 82333-41-3
8-amino-6-methoxy-4-methyl-5-(3-trifluoromethylphenoxy)quinoline

: 83547-30-2
6-bromo-N-<6-methoxy-4-methyl-5-<3-(trifluoromethyl)phenoxy>-8-quinolinyl>hexanamide

Guidance literature:: With sodium carbonate; In acetone; for 3h; Heating;
DOI:10.1021/jm00356a013

Reference yield:

: 83547-30-2
6-bromo-N-<6-methoxy-4-methyl-5-<3-(trifluoromethyl)phenoxy>-8-quinolinyl>hexanamide

: 83547-24-4
N-Isopropyl-N'-[6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-hexane-1,6-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: benzene / Heating

2: 35 percent / AlCl₃, LiAlH₄ / tetrahydrofuran / -20 - 0 °C

With lithium aluminium tetrahydride; aluminium trichloride; In tetrahydrofuran; benzene;
DOI:10.1021/jm00356a013

Reference yield:

: 83547-30-2
6-bromo-N-<6-methoxy-4-methyl-5-<3-(trifluoromethyl)phenoxy>-8-quinolinyl>hexanamide

: 83547-21-1
2-(4-{6-[6-Methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-ylamino]-hexyl}-piperazin-1-yl)-ethanol; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: benzene / Heating

2: 53 percent / AlCl₃, LiAlH₄ / tetrahydrofuran / -20 - 0 °C

With lithium aluminium tetrahydride; aluminium trichloride; In tetrahydrofuran; benzene;
DOI:10.1021/jm00356a013