cis-4-((R)-5-methyl-2-oxooxazolidin-3-yl)cyclohexanecarboxylic acid methyl ester

Base Information

Chemical Name:cis-4-((R)-5-methyl-2-oxooxazolidin-3-yl)cyclohexanecarboxylic acid methyl ester
CAS No.:1579977-34-6
Molecular Formula:C₁₂H₁₉NO₄
Molecular Weight:241.287
Hs Code.:

Synonyms:cis-4-((R)-5-methyl-2-oxooxazolidin-3-yl)cyclohexanecarboxylic acid methyl ester

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Chemical Property of cis-4-((R)-5-methyl-2-oxooxazolidin-3-yl)cyclohexanecarboxylic acid methyl ester

Chemical Property:

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Technology Process of cis-4-((R)-5-methyl-2-oxooxazolidin-3-yl)cyclohexanecarboxylic acid methyl ester

There total 3 articles about cis-4-((R)-5-methyl-2-oxooxazolidin-3-yl)cyclohexanecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-44-5
phosgene

: cis-4-((R)-2-hydroxypropylamino)cyclohexanecarboxylic acid methyl ester

: 1579977-34-6
cis-4-((R)-5-methyl-2-oxooxazolidin-3-yl)cyclohexanecarboxylic acid methyl ester

Guidance literature:: In dichloromethane; toluene; at 20 ℃; for 12h;
DOI:10.1016/j.bmcl.2014.02.023

Reference yield:

: 61367-16-6
cis-4-aminocyclohexanecarboxylic acid methyl ester hydrochloride

: 1579977-34-6
cis-4-((R)-5-methyl-2-oxooxazolidin-3-yl)cyclohexanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / dichloromethane / 1 h / 20 °C

2: ethanol / 3 h / 65 °C

3: dichloromethane; toluene / 12 h / 20 °C

With potassium carbonate; In ethanol; dichloromethane; toluene;
DOI:10.1016/j.bmcl.2014.02.023

Reference yield:

: 62456-15-9,75143-07-6
methyl (1s,4s)-4-aminocyclohexane-1-carboxylate

: 1579977-34-6
cis-4-((R)-5-methyl-2-oxooxazolidin-3-yl)cyclohexanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 3 h / 65 °C

2: dichloromethane; toluene / 12 h / 20 °C

In ethanol; dichloromethane; toluene;
DOI:10.1016/j.bmcl.2014.02.023