(2S,4S)-2,4-dihydroxypentane-1,5-diyl bis(2,4,6-tri-isopropylbenzenesulphonate)

Base Information

• Chemical Name: (2S,4S)-2,4-dihydroxypentane-1,5-diyl bis(2,4,6-tri-isopropylbenzenesulphonate)
• CAS No.: 92512-29-3
• Molecular Formula: C₃₅H₅₆O₈S₂
• Molecular Weight: 668.957
• Mol file: 92512-29-3.mol

Synonyms:(2S,4S)-2,4-dihydroxypentane-1,5-diyl bis(2,4,6-tri-isopropylbenzenesulphonate)

Chemical Property of (2S,4S)-2,4-dihydroxypentane-1,5-diyl bis(2,4,6-tri-isopropylbenzenesulphonate)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,4S)-2,4-dihydroxypentane-1,5-diyl bis(2,4,6-tri-isopropylbenzenesulphonate)

There total 10 articles about (2S,4S)-2,4-dihydroxypentane-1,5-diyl bis(2,4,6-tri-isopropylbenzenesulphonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2,4,6-tri-isopropylbenzenesulphonyl chloride + (2S,4S)-pentane-1,2,4,5-tetraol (17609-05-1,41107-44-2,89617-06-1,92691-36-6) → (2S,4S)-2,4-dihydroxypentane-1,5-diyl bis(2,4,6-tri-isopropylbenzenesulphonate) (92512-29-3)

Guidance literature:

With pyridine; at 5 ℃;

Reference yield: 85.0%

2,4,6-triisopropylphenylsulfonyl chloride (6553-96-4) + (2S,4S)-pentane-1,2,3,4-tetraol (92691-36-6) → (2S,4S)-2,4-dihydroxypentane-1,5-diyl bis(2,4,6-triisopropyl-1-benzenesulfonate) (92512-29-3)

Guidance literature:

With pyridine; at 20 ℃; for 16h;

DOI:10.1021/jo034374x

Reference yield:

Bis-((R)-2,2-diethyl-[1,3]dioxolan-4-yl)-methanol (457630-79-4) → (2S,4S)-2,4-dihydroxypentane-1,5-diyl bis(2,4,6-triisopropyl-1-benzenesulfonate) (92512-29-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 100 percent / 1,2-dichloro-ethane / 6 h / Heating

2: 93 percent / Et₃SiH; benzoyl peroxide / 2 h / Heating

3: 96 percent / aq. H₂SO₄ / ethanol / 4 h / Heating

4: 85 percent / pyridine / 16 h / 20 °C

With pyridine; triethylsilane; sulfuric acid; dibenzoyl peroxide; In ethanol; 1,2-dichloro-ethane;

DOI:10.1021/jo034374x

upstream raw materials:

2,4,6-triisopropylphenylsulfonyl chloride

(2S,4S)-pentane-1,2,3,4-tetraol

Bis-((R)-2,2-diethyl-[1,3]dioxolan-4-yl)-methanol

(2S,4S)-di-O-(3,3-pentylidene)-3-deoxyarabitol

Downstream raw materials:

(3S,5S)-3,5-bis(benzoyloxy)heptane-1,7-dinitrile

(+)-<2R(2E,4R),4S,6S,8R,9S>-2-<6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol

(+)-α-<6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-hexenyl>oxiraneethanol

(2S,4S)-1,2:4,5-dianhydro-3-deoxypentitol