3-(4-chlorophenyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid

Base Information

• Chemical Name: 3-(4-chlorophenyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid
• CAS No.: 194471-87-9
• Molecular Formula: C24H20 Cl N O4
• Molecular Weight: 421.87
• DSSTox Substance ID: DTXSID00377360
• Mol file: 194471-87-9.mol

Synonyms:194471-87-9;3-(4-chlorophenyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid;3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-chlorophenyl)propanoic acid;3-(4-chlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid;3-(4-Chlorophenyl)-3-{[(9H-fluoren-9-ylmethoxy)-carbonyl]amino}propanoic acid;3-(4-CHLOROPHENYL)-3-({[(9H-FLUOREN-9-YL)METHOXY]CARBONYL}AMINO)PROPANOIC ACID;Fmoc-(S)-3-Amino-3-(4-chlorophenyl)propionic acid;MFCD03428036;Fmoc-(R)-3-Amino-3-(4-chloro-phenyl)-propionic acid;N-Fmoc-DL-3-(4-chlorophenyl)-3-amino-propionic aicd;DTXSID00377360;VDMPMJZDURHZTB-UHFFFAOYSA-N;MFCD01863197;AKOS005070923;Benzenepropanoic acid,4-chloro-b-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-;AB15323;AB15399;AC-12819;SY106950;CS-0345532;FT-0656268;FT-0657005;FT-0680540;EN300-650294;6Y-0928;J-510367;(R)-3-(Fmoc-amino)-3-(4-chlorophenyl)propanoic Acid;N-Fmoc-DL-3-(4-chlorophenyl)-3-amino-propionic acid, AldrichCPR

Chemical Property of 3-(4-chlorophenyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid

Chemical Property:

• Vapor Pressure: 2.27E-17mmHg at 25°C
• Melting Point: 193-195°
• Boiling Point: 642.2°Cat760mmHg
• Flash Point: 342.2°C
• PSA: 75.63000
• Density: 1.336g/cm³
• LogP: 5.78540
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 421.1080858
• Heavy Atom Count: 30
• Complexity: 584

Purity/Quality:

98%min ^*data from raw suppliers

3-(4-Chlorophenyl)-3-{[(9H-fluoren-9-ylmethoxy)-carbonyl]amino}propanoic acid >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC(=O)O)C4=CC=C(C=C4)Cl

Technology Process of 3-(4-chlorophenyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid

There total 1 articles about 3-(4-chlorophenyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(fluorenylmethoxy)carbonyl chloride (28920-43-6) + 3-amino-3-(4-chlorophenyl)propionic acid (19947-39-8,131690-61-4) → 3-[N-(9H-fluoren-9-ylmethoxycarbonyl)-amino]-3-(4-chloro)-phenylorpionic acid (194471-87-9,479064-92-1)

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; water; at 20 ℃; for 24h;

DOI:10.1021/jm0004953

upstream raw materials:

(fluorenylmethoxy)carbonyl chloride

3-amino-3-(4-chlorophenyl)propionic acid

Refernces