N-(1-phenylethyl)hydroxylamine

Base Information

• Chemical Name: N-(1-phenylethyl)hydroxylamine
• CAS No.: 2912-98-3
• Molecular Formula: C8H11NO
• Molecular Weight: 137.181
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID20456060
• Nikkaji Number: J1.498.769J
• Mol file: 2912-98-3.mol

Synonyms:N-(1-phenylethyl)hydroxylamine;2912-98-3;MFCD06660399;N-(1-Phenyl-ethyl)-hydroxylamine;1-phenylethylhydroxylamine;SCHEMBL3044206;N-(1-Phenylethyl)-hydroxylamine;1-(Hydroxyamino)-1-phenylethane;DTXSID20456060;CAA91298;2-CYANO-4-PYRIDINEACETICACID;AKOS005257485;SB11664;SB11665;Benzenemethanamine, N-hydroxy-|A-methyl-;FT-0690228;BENZENEMETHANAMINE,N-HYDROXY-A-METHYL-;EN300-129680;N-(1-PYRIDIN-4-YL-ETHYL)-HYDROXYLAMINE;DIMETHYL1-(2-BROMOETHYL)-1H-PYRAZOLE-3,5-DICARBOXYLATE

Chemical Property of N-(1-phenylethyl)hydroxylamine

Chemical Property:

• Vapor Pressure: 0.011mmHg at 25°C
• Refractive Index: 1.546
• Boiling Point: 250.858 °C at 760 mmHg
• Flash Point: 117.221 °C
• PSA: 32.26000
• Density: 1.061 g/cm³
• LogP: 2.11730
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 137.084063974
• Heavy Atom Count: 10
• Complexity: 89.3

Purity/Quality:

99% ^*data from raw suppliers

N-(1-Phenylethyl)hydroxylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=CC=C1)NO

Technology Process of N-(1-phenylethyl)hydroxylamine

There total 31 articles about N-(1-phenylethyl)hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

acetophenone oxime (613-91-2) → N-(1-phenyl-ethyl)-hydroxylamine (2912-98-3,53933-47-4,67377-55-3,101314-62-9)

Guidance literature:

With Benzyltriethylammonium borohydride; at 20 ℃; for 0.216667h; solid-phase conditions;

DOI:10.1070/MC2006v016n01ABEH002213

Reference yield: 77.0%

N-(1-phenylethyl)-O-(triisopropylsilyl)hydroxylamine → N-(1-phenyl-ethyl)-hydroxylamine (2912-98-3,53933-47-4,67377-55-3,101314-62-9)

Guidance literature:

With pyridine hydrogenfluoride; In tetrahydrofuran; at 0 ℃; for 3h;

DOI:10.1002/anie.201407324

Reference yield: 75.0%

N-α-methyl benzyl-O-benzoyl hydroxylamine hydrochloride (127104-39-6) → N-(1-phenyl-ethyl)-hydroxylamine (2912-98-3,53933-47-4,67377-55-3,101314-62-9)

Guidance literature:

With sodium hydroxide; In methanol; at 60 ℃; for 0.25h;

DOI:10.1021/jo00298a018

upstream raw materials:

acetophenone oxime

N-α-methyl benzyl-O-benzoyl hydroxylamine hydrochloride

tin(II) benzenethiolate

(1-nitroethyl)benzene

Downstream raw materials:

N-(1-phenylethyl)-N-hydroxyurea

N-benzylidene-1-phenylethanamine N-oxide

(+/-)-N-(2-methylpropylidene)-1-phenylethanamine N-oxide

N-(1-phenylethyl)-O-thiopivaloylhydroxylamine