5-(2-Furyl)-1-phenyl-1H-pyrazole-3-carboxylic acid

Base Information

Chemical Name:5-(2-Furyl)-1-phenyl-1H-pyrazole-3-carboxylic acid
CAS No.:100537-55-1
Molecular Formula:C14H10N2O3
Molecular Weight:254.245
Hs Code.:2934999090
DSSTox Substance ID:DTXSID70377978
Wikidata:Q82167392
Mol file:100537-55-1.mol

Synonyms:100537-55-1;5-(2-Furyl)-1-phenyl-1H-pyrazole-3-carboxylic acid;5-(Furan-2-yl)-1-phenyl-1H-pyrazole-3-carboxylic acid;5-(furan-2-yl)-1-phenylpyrazole-3-carboxylic acid;MFCD06245333;1H-Pyrazole-3-carboxylic acid, 5-(2-furanyl)-1-phenyl-;SCHEMBL1816556;DTXSID70377978;DYXLCKGZAKVTAF-UHFFFAOYSA-N;BBL103582;STL557392;AKOS000155959;FT-0729185;3-(2-CHLORO-4-FLUORO-PHENYL)-PROPIONICACID;5-(Fur-2-yl)-1-phenyl-1H-pyrazole-3-carboxylic acid;5-(2-Furyl)-1-phenyl-1H-pyrazole-3-carboxylic acid, AldrichCPR

Suppliers and Price of 5-(2-Furyl)-1-phenyl-1H-pyrazole-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
5-(Fur-2-yl)-1-phenyl-1H-pyrazole-3-carboxylic acid
500 mg
$ 240.00

Apolloscientific
5-(Fur-2-yl)-1-phenyl-1H-pyrazole-3-carboxylic acid
500mg
$ 203.00

American Custom Chemicals Corporation
5-(2-FURYL)-1-PHENYL-1H-PYRAZOLE-3-CARBOXYLIC ACID 95.00%
500MG
$ 795.80

Total 15 raw suppliers

Chemical Property of 5-(2-Furyl)-1-phenyl-1H-pyrazole-3-carboxylic acid

Chemical Property:

Vapor Pressure:7.82E-10mmHg at 25°C
Melting Point:166 °C
Refractive Index:1.656
Boiling Point:475.1 °C at 760 mmHg
PKA:3.86±0.10(Predicted)
Flash Point:241.1 °C
PSA：68.26000
Density:1.34 g/cm³
LogP:2.83050
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:254.06914219
Heavy Atom Count:19
Complexity:331

Purity/Quality:

97% ^*data from raw suppliers

5-(Fur-2-yl)-1-phenyl-1H-pyrazole-3-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C(=CC(=N2)C(=O)O)C3=CC=CO3

Technology Process of 5-(2-Furyl)-1-phenyl-1H-pyrazole-3-carboxylic acid

There total 6 articles about 5-(2-Furyl)-1-phenyl-1H-pyrazole-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 101351-11-5
3-ethoxycarbonyl-5-(2-furyl)-1-phenylpyrazole

: 100537-55-1
5-[2]furyl-1-phenyl-1H-pyrazole-3-carboxylic acid

Guidance literature:: With sodium hydroxide; In methanol; water; Inert atmosphere;
DOI:10.1016/j.cclet.2017.10.011

Reference yield:

: 1192-62-7,80145-44-4
1-(2-furyl)-1-ethanone

: 100537-55-1
5-[2]furyl-1-phenyl-1H-pyrazole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: sodium; diethyl ether

2: acetic acid; N₂H₄+H₂O

3: diethyl ether

4: ethanolic KOH

With potassium hydroxide; diethyl ether; sodium; hydrazine hydrate; acetic acid;

Reference yield:

: 100-63-0
phenylhydrazine

: 100537-55-1
5-[2]furyl-1-phenyl-1H-pyrazole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium / ethanol / 0 - 20 °C / Inert atmosphere

1.2: Inert atmosphere

2.1: sodium hydroxide / water; methanol / Inert atmosphere

With sodium; sodium hydroxide; In methanol; ethanol; water;
DOI:10.1016/j.cclet.2017.10.011